Sugar addiction: from evolution to revolution

DA Wiss, N Avena, P Rada - Frontiers in psychiatry, 2018 - frontiersin.org
The obesity epidemic has been widely publicized in the media worldwide. Investigators at all
levels have been looking for factors that have contributed to the development of this …

Dopamine, effort-based choice, and behavioral economics: basic and translational research

JD Salamone, M Correa, JH Yang, R Rotolo… - Frontiers in behavioral …, 2018 - frontiersin.org
Operant behavior is not only regulated by factors related to the quality or quantity of
reinforcement, but also by the work requirements inherent in performing instrumental …

Modulatory effect of gut microbiota on the gut-brain, gut-bone axes, and the impact of cannabinoids

I Ibrahim, S Syamala, JA Ayariga, J Xu, BK Robertson… - Metabolites, 2022 - mdpi.com
The gut microbiome is a collection of microorganisms and parasites in the gastrointestinal
tract. Many factors can affect this community's composition, such as age, sex, diet …

The psychopharmacology of effort-related decision making: dopamine, adenosine, and insights into the neurochemistry of motivation

JD Salamone, M Correa, S Ferrigno, JH Yang… - Pharmacological …, 2018 - ASPET
Effort-based decision making is studied using tasks that offer choices between high-effort
options leading to more highly valued reinforcers versus low-effort/low-reward options …

Complexities and paradoxes in understanding the role of dopamine in incentive motivation and instrumental action: exertion of effort vs. anhedonia

JD Salamone, A Ecevitoglu, C Carratala-Ros… - Brain Research …, 2022 - Elsevier
Instrumental behavior is a very complex and multifaceted process. Behavioral output during
instrumental performance is influenced by a variety of factors, including associative …

Coordinated reductions in excitatory input to the nucleus accumbens underlie food consumption

SJ Reed, CK Lafferty, JA Mendoza, AK Yang… - Neuron, 2018 - cell.com
Reward-seeking behavior is regulated by a diverse collection of inputs to the nucleus
accumbens (NAc). The information encoded in each excitatory afferent to the NAc is …

[HTML][HTML] Dissociable contributions of phasic dopamine activity to reward and prediction

WX Pan, LT Coddington, JT Dudman - Cell Reports, 2021 - cell.com
Sensory cues that precede reward acquire predictive (expected value) and incentive (drive
reward-seeking action) properties. Mesolimbic dopamine neurons' responses to sensory …

Orexin in the posterior paraventricular thalamus mediates hunger-related signals in the nucleus accumbens core

J Meffre, M Sicre, M Diarra, F Marchessaux… - Current Biology, 2019 - cell.com
Animals use exteroceptive stimuli that have acquired, through learning, the ability to predict
available resources allowing them to engage in adaptive behaviors. Meanwhile, peripheral …

Chronic high-fat diet affects food-motivated behavior and hedonic systems in the nucleus accumbens of male rats

DM Arcego, R Krolow, C Lampert, AP Toniazzo… - Appetite, 2020 - Elsevier
Environmental variations can influence eating and motivated behaviors, as well as the
brain's feeding circuits to predisposing overweight and obesity. The identification of …

Dopamine and proximity in motivation and cognitive control

A Westbrook, M Frank - Current Opinion in Behavioral Sciences, 2018 - Elsevier
Highlights•Striatal dopamine can both promote cognitive control and undermine it.•Opposing
effects may be resolved considering striatal action selection biases.•Dopamine may …