Immunotherapy, inflammation and colorectal cancer

CR Lichtenstern, RK Ngu, S Shalapour, M Karin - Cells, 2020 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer type, and third highest in mortality
rates among cancer-related deaths in the United States. Originating from intestinal epithelial …

[HTML][HTML] Emerging roles of Wnt ligands in human colorectal cancer

X Nie, H Liu, L Liu, YD Wang, WD Chen - Frontiers in oncology, 2020 - frontiersin.org
Colorectal cancer (CRC) is the fourth leading cause of cancer death worldwide, and
constitutive activation of the Wnt signaling pathway is universal in most CRC cases. Wnt …

Emerging trends in colorectal cancer: Dysregulated signaling pathways

R Ahmad, JK Singh, A Wunnava… - International …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer‑related mortality globally. The American Cancer Society …

LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer

K Luo, J Geng, Q Zhang, Y Xu, X Zhou, Z Huang… - Journal of Experimental …, 2019 - Springer
Background Colorectal cancer (CRC) is the third most frequent cancer and the second
leading cause of cancer-related death worldwide. Increasing evidence indicates that the …

An update on colorectal cancer microenvironment, epigenetic and immunotherapy

K Jin, C Ren, Y Liu, H Lan, Z Wang - International immunopharmacology, 2020 - Elsevier
Colorectal cancer (CRC) is considered as the second most common cancer worldwide. For
the past few years, the role of immunotherapy has been extensively studied and it has been …

Therapeutic effects of curcumol in several diseases; an overview

S Hashem, S Nisar, G Sageena, MA Macha… - Nutrition and …, 2021 - Taylor & Francis
Curcumae Rhizoma, also known as Ezhu is a traditional Chinese medicine that has been
used for many centuries against several diseases. The rhizome of the plant is composed of …

LDL, HDL and endocrine-related cancer: From pathogenic mechanisms to therapies

G Revilla, L Cedó, M Tondo, A Moral, JI Pérez… - Seminars in Cancer …, 2021 - Elsevier
Cholesterol is essential for a variety of functions in endocrine-related cells, including
hormone and steroid production. We have reviewed the progress to date in research on the …

[HTML][HTML] Regulatory RNAs, microRNA, long-non coding RNA and circular RNA roles in colorectal cancer stem cells

HM Chao, TW Wang, E Chern, S Hsu - World Journal of …, 2022 - ncbi.nlm.nih.gov
The properties of cancer stem cells (CSCs), such as self-renewal, drug resistance, and
metastasis, have been indicated to be responsible for the poor prognosis of patients with …

Isobavachalcone isolated from Psoralea corylifolia inhibits cell proliferation and induces apoptosis via inhibiting the AKT/GSK-3β/β-catenin pathway in colorectal …

Y Li, X Qin, P Li, H Zhang, T Lin, Z Miao… - Drug design …, 2019 - Taylor & Francis
Background: Colorectal cancer (CRC) is a common form of cancer associated with a high
mortality rate and poor prognosis. Given the limited efficacy of current therapies for CRC …

Integrated analysis of necroptosis-related genes for evaluating immune infiltration and colon cancer prognosis

W Yang, S Lu, L Peng, Z Zhang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background Colon cancer (CC) is the second most common gastrointestinal malignancy.
About one in five patients have already developed distant metastases at the time of initial …