Neurotoxicity of pesticides

JR Richardson, V Fitsanakis, RHS Westerink… - Acta …, 2019 - Springer
Pesticides are unique environmental contaminants that are specifically introduced into the
environment to control pests, often by killing them. Although pesticide application serves …

Organophosphorus xenobiotic toxicology

JE Casida - Annual review of pharmacology and toxicology, 2017 - annualreviews.org
Originally, organophosphorus (OP) toxicology consisted of acetylcholinesterase inhibition by
insecticides and chemical threat agents acting as phosphorylating agents for serine in the …

Herbicides glyphosate and glufosinate ammonium negatively affect human sperm mitochondria respiration efficiency

A Ferramosca, S Lorenzetti, M Di Giacomo… - Reproductive …, 2021 - Elsevier
The widespread cultivation of genetically modified organisms (GMOs) led to a widespread
use of selective herbicides to which GMOs are resistant, thus increasing the concern about …

Integration of toxicodynamic and toxicokinetic new approach methods into a weight-of-evidence analysis for pesticide developmental neurotoxicity assessment: A …

S Dobreniecki, E Mendez, A Lowit… - Regulatory Toxicology …, 2022 - Elsevier
Abstract DL-glufosinate ammonium (DL-GLF) is a registered herbicide for which a guideline
Developmental Neurotoxicity (DNT) study has been conducted. Offspring effects included …

The potential of in vitro neuronal networks cultured on micro electrode arrays for biomedical research

M Cerina, MC Piastra, M Frega - Progress in Biomedical …, 2023 - iopscience.iop.org
In vitro neuronal models have become an important tool to study healthy and diseased
neuronal circuits. The growing interest of neuroscientists to explore the dynamics of …

Sub-acute toxicity of the herbicide glufosinate-ammonium exposure in adult red swamp crayfish (Procambarus clarkii)

Y Zhang, Y Dang, F Pei, Y Yuan, J Yuan, Z Gu… - Environmental …, 2023 - Elsevier
Glufosinateammonium (GLA) is one of the most widely used agricultural herbicides. It is
frequently detected in surface waters near farmland and may pose a risk to non-target …

Concentration–response evaluation of ToxCast compounds for multivariate activity patterns of neural network function

MB Kosnik, JD Strickland, SW Marvel, DJ Wallis… - Archives of …, 2020 - Springer
Abstract The US Environmental Protection Agency's ToxCast program has generated toxicity
data for thousands of chemicals but does not adequately assess potential neurotoxicity …

Perinatal Exposure to the Cyanotoxin β-N-Méthylamino-l-Alanine (BMAA) Results in Long-Lasting Behavioral Changes in Offspring—Potential Involvement of DNA …

A Laugeray, A Oummadi, C Jourdain, J Feat… - Neurotoxicity …, 2018 - Springer
We recently demonstrated that perinatal exposure to the glutamate-related herbicide,
glufosinate ammonium, has deleterious effects on neural stem cell (NSC) homeostasis …

Immunofluorescence/fluorescence assessment of brain-derived neurotrophic factor, c-Fos activation, and apoptosis in the brain of zebrafish (Danio rerio) larvae …

S Çomakli, M Köktürk, A Topal, M Özkaraca… - Neurotoxicology, 2018 - Elsevier
In this study, we investigated the potential neuro-toxicological mechanism of the glufosinate
in the brain of zebrafish larvae in terms of BDNF and c-Fos proteins by evaluating apoptosis …

Hepatotoxicity and reproductive disruption in male lizards (Eremias argus) exposed to glufosinate-ammonium contaminated soil

L Zhang, J Diao, L Chen, Z Wang, W Zhang, Y Li… - Environmental …, 2019 - Elsevier
Glufosinate-ammonium (GLA) is a spectrum herbicide that is widely used in agriculture. The
toxic effects of GLA on plants and mammals have been extensively studied; however, little is …