Preoperative local anesthetic blockade of somatosensory pathways involved with skin
incision and other noxious perioperative stimuli may" preempt" or attenuate the …

With recent developments in the field of analgesia, the question arises whether there is a
role for placing local anesthetics, nonsteroidal anti-inflammatory drugs, or both into the …

We have compared in 25 children the effect of preoperative with postoperative caudal block
on pain after circumcision in a double-blind, randomized study. After induction of …

Recent studies concerned with the relationship between injury responses and acute and
chronic pain were reviewed. Basic and clinical studies of pain have revealed that a large …

As more outpatient orthopaedic surgical procedures are performed, postoperative pain
control has gained importance. The benefits of preemptive analgesia, the use of analgesics …

Background: Although promising in experimental studies of post‐traumatic pain, the concept
of pre‐emptive analgesia is still controversial in a clinical setting. Thus, we wanted to …

Pre-emptive treatment with an iv infusion of morphine 10 mg at induction reduces
postoperative analgesic requirement and wound hypersensitivity compared with the same …

Patients undergoing extractions of third molar teeth under general anesthesia were given a
placebo, diclofenac (a nonsteroidal anti-inflammatory drug) 100 mg, or methadone (an …

AIM Vitrectomies are performed either under general anesthesia (GA), local anesthesia (LA),
or a combination of both. Postoperative pain is expected to be less in patients with LA …

Recent evidence suggests that surgical trauma induces a process of central nervous system
sensitisation that contributes to and enhances postoperative pain. These changes are also …