American Association of Clinical Endocrinology clinical practice guideline for the diagnosis and management of nonalcoholic fatty liver disease in primary care and …
K Cusi, S Isaacs, D Barb, R Basu, S Caprio… - Endocrine Practice, 2022 - Elsevier
Objective To provide evidence-based recommendations regarding the diagnosis and
management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis …
management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis …
Challenges and opportunities in NASH drug development
SA Harrison, AM Allen, J Dubourg, M Noureddin… - Nature medicine, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and its more severe form, nonalcoholic
steatohepatitis (NASH), represent a growing worldwide epidemic and a high unmet medical …
steatohepatitis (NASH), represent a growing worldwide epidemic and a high unmet medical …
EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …
Emerging therapeutic approaches for the treatment of NAFLD and type 2 diabetes mellitus
D Ferguson, BN Finck - Nature Reviews Endocrinology, 2021 - nature.com
Non-alcoholic fatty liver disease (NAFLD) has emerged as the most prevalent liver disease
in the world, yet there are still no approved pharmacological therapies to prevent or treat this …
in the world, yet there are still no approved pharmacological therapies to prevent or treat this …
Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis
FE Mózes, JA Lee, EA Selvaraj, ANA Jayaswal… - Gut, 2022 - gut.bmj.com
Objective Liver biopsy is still needed for fibrosis staging in many patients with non-alcoholic
fatty liver disease. The aims of this study were to evaluate the individual diagnostic …
fatty liver disease. The aims of this study were to evaluate the individual diagnostic …
Current therapies and new developments in NASH
Non-alcoholic steatohepatitis is becoming the most important aetiology for advanced liver
disease. There has been important progress in the field in recent years and the complexity of …
disease. There has been important progress in the field in recent years and the complexity of …
Impact of non-invasive biomarkers on hepatology practice: past, present and future
Over the last two decades, there have been tremendous advances in the non-invasive
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …
diagnosis and risk stratification of chronic liver diseases (CLDs). Non-invasive approaches …
Therapeutic pipeline in nonalcoholic steatohepatitis
R Vuppalanchi, M Noureddin, N Alkhouri… - Nature reviews …, 2021 - nature.com
Our understanding of nonalcoholic fatty liver disease pathophysiology continues to advance
rapidly. Accordingly, the field has moved from describing the clinical phenotype through the …
rapidly. Accordingly, the field has moved from describing the clinical phenotype through the …
Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD
Hepatic steatosis is a key histological feature of nonalcoholic fatty liver disease (NAFLD).
The non-invasive quantification of liver fat is now possible due to advances in imaging …
The non-invasive quantification of liver fat is now possible due to advances in imaging …
Advanced liver fibrosis is common in patients with type 2 diabetes followed in the outpatient setting: the need for systematic screening
R Lomonaco, E Godinez Leiva, F Bril… - Diabetes …, 2021 - Am Diabetes Assoc
OBJECTIVE Assess the prevalence of nonalcoholic fatty liver disease (NAFLD) and of liver
fibrosis associated with nonalcoholic steatohepatitis in unselected patients with type 2 …
fibrosis associated with nonalcoholic steatohepatitis in unselected patients with type 2 …