Dissecting the biology of feeding and eating disorders
Feeding and eating disorders (FEDs) are heterogenous and characterized by varying
patterns of dysregulated eating and weight. Genome-wide association studies (GWASs) are …
patterns of dysregulated eating and weight. Genome-wide association studies (GWASs) are …
Schizophrenia polygenic risk scores, clinical variables and genetic pathways as predictors of phenotypic traits of bipolar I disorder
M Grigoroiu-Serbanescu, T Van der Veen… - Journal of Affective …, 2024 - Elsevier
Aim We investigated the predictive value of polygenic risk scores (PRS) derived from the
schizophrenia GWAS (Trubetskoy et al., 2022)(SCZ3) for phenotypic traits of bipolar disorder …
schizophrenia GWAS (Trubetskoy et al., 2022)(SCZ3) for phenotypic traits of bipolar disorder …
[PDF][PDF] Better together: Non-additive interactions between schizophrenia risk genes
PJM Deans, KJ Brennand - Cell Genomics, 2023 - cell.com
Zhang, Zhang, Forrest et al combine allele-specific open chromatin (ASoC) mapping and
CRISPR-editing to evaluate the functional impact of schizophrenia risk variants on human …
CRISPR-editing to evaluate the functional impact of schizophrenia risk variants on human …
Schizophrenia risk gene ZNF804A controls ribosome localization and synaptogenesis in developing human neurons
L Sichlinger, M Wulf, L Dutan Polit, F Nasser… - bioRxiv, 2024 - biorxiv.org
ZNF804A was amongst the first genes robustly associated with schizophrenia based on
findings from large-scale genomic studies. Previous research has implicated ZNF804A in …
findings from large-scale genomic studies. Previous research has implicated ZNF804A in …