High‐Precision Synthesis of RNA‐Loaded Lipid Nanoparticles for Biomedical Applications

H Seo, L Jeon, J Kwon, H Lee - Advanced Healthcare …, 2023 - Wiley Online Library
The recent development of RNA‐based therapeutics in delivering nucleic acids for gene
editing and regulating protein translation has led to the effective treatment of various …

Chronic hepatitis C: Acute exacerbation and alanine aminotransferase flare

T Kanda, N Matsumoto, T Ishii, S Arima, S Shibuya… - Viruses, 2023 - mdpi.com
The hepatitis C virus (HCV) causes acute and chronic hepatitis, cirrhosis, and hepatocellular
carcinoma, as well as extrahepatic manifestations such as malignant lymphoma. Currently …

Common carp (Cyprinus carpio) CD81 promoting CyHV-3 virus replication via regulating autophagy and RLRs-interferon signaling pathway

X Lee, Z Fan, Z Huang, M Guo, D Peng, W Luo… - Fish & Shellfish …, 2023 - Elsevier
Abstract Cyprinid herpesvirus type 3 (CyHV-3), also called Koi herpesvirus (KHV), which
leads to mass cyprinid mortality and enormous economic losses. To establish an infection …

Hepatitis C virus modified sE2F442NYT as an antigen in candidate vaccine facilitates human immune cell activation

Y Haga, K Meyer, MMH Sung, EK Reagan… - Journal of …, 2024 - Am Soc Microbiol
The rational selection of hepatitis C virus (HCV) vaccine antigen will aid in the prevention of
future chronic liver disease burden and associated healthcare costs. We have previously …

Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development

BG Pierce, N Felbinger, M Metcalf, EA Toth, G Ofek… - Viruses, 2024 - mdpi.com
Hepatitis C virus (HCV) is a major medical health burden and the leading cause of chronic
liver disease and cancer worldwide. More than 58 million people are chronically infected …

RNA nanomedicine in liver diseases

A Bakrania, Y Mo, G Zheng, M Bhat - Hepatology, 2023 - journals.lww.com
The remarkable impact of RNA nanomedicine during the COVID-19 pandemic has
demonstrated the expansive therapeutic potential of this field in diverse disease contexts. In …

Hepatitis C virus E1 and modified E2 delivered from an mRNA vaccine induces protective immunity

T Patra, K Meyer, Y Haga, EK Reagan, D Weissman… - npj Vaccines, 2023 - nature.com
Hepatitis C virus (HCV) is characterized by a high number of chronic cases due to an
impairment of protective innate and adaptive immune responses. Here, we examined the …

Events Sequence Beyond mRNA Spike (S) Protein Vaccine and Long COVID: Simply Targeting Brain?

M Altable - Available at SSRN 4733090, 2024 - papers.ssrn.com
The intricate mechanisms of the immune response elicited by vaccines and the interplay
between the immune system and the central nervous system (CNS) are poorly understood …