High‐Precision Synthesis of RNA‐Loaded Lipid Nanoparticles for Biomedical Applications
The recent development of RNA‐based therapeutics in delivering nucleic acids for gene
editing and regulating protein translation has led to the effective treatment of various …
editing and regulating protein translation has led to the effective treatment of various …
Chronic hepatitis C: Acute exacerbation and alanine aminotransferase flare
T Kanda, N Matsumoto, T Ishii, S Arima, S Shibuya… - Viruses, 2023 - mdpi.com
The hepatitis C virus (HCV) causes acute and chronic hepatitis, cirrhosis, and hepatocellular
carcinoma, as well as extrahepatic manifestations such as malignant lymphoma. Currently …
carcinoma, as well as extrahepatic manifestations such as malignant lymphoma. Currently …
Common carp (Cyprinus carpio) CD81 promoting CyHV-3 virus replication via regulating autophagy and RLRs-interferon signaling pathway
X Lee, Z Fan, Z Huang, M Guo, D Peng, W Luo… - Fish & Shellfish …, 2023 - Elsevier
Abstract Cyprinid herpesvirus type 3 (CyHV-3), also called Koi herpesvirus (KHV), which
leads to mass cyprinid mortality and enormous economic losses. To establish an infection …
leads to mass cyprinid mortality and enormous economic losses. To establish an infection …
Hepatitis C virus modified sE2F442NYT as an antigen in candidate vaccine facilitates human immune cell activation
Y Haga, K Meyer, MMH Sung, EK Reagan… - Journal of …, 2024 - Am Soc Microbiol
The rational selection of hepatitis C virus (HCV) vaccine antigen will aid in the prevention of
future chronic liver disease burden and associated healthcare costs. We have previously …
future chronic liver disease burden and associated healthcare costs. We have previously …
Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development
Hepatitis C virus (HCV) is a major medical health burden and the leading cause of chronic
liver disease and cancer worldwide. More than 58 million people are chronically infected …
liver disease and cancer worldwide. More than 58 million people are chronically infected …
RNA nanomedicine in liver diseases
The remarkable impact of RNA nanomedicine during the COVID-19 pandemic has
demonstrated the expansive therapeutic potential of this field in diverse disease contexts. In …
demonstrated the expansive therapeutic potential of this field in diverse disease contexts. In …
Hepatitis C virus E1 and modified E2 delivered from an mRNA vaccine induces protective immunity
T Patra, K Meyer, Y Haga, EK Reagan, D Weissman… - npj Vaccines, 2023 - nature.com
Hepatitis C virus (HCV) is characterized by a high number of chronic cases due to an
impairment of protective innate and adaptive immune responses. Here, we examined the …
impairment of protective innate and adaptive immune responses. Here, we examined the …
Events Sequence Beyond mRNA Spike (S) Protein Vaccine and Long COVID: Simply Targeting Brain?
M Altable - Available at SSRN 4733090, 2024 - papers.ssrn.com
The intricate mechanisms of the immune response elicited by vaccines and the interplay
between the immune system and the central nervous system (CNS) are poorly understood …
between the immune system and the central nervous system (CNS) are poorly understood …