[HTML][HTML] Molecular mechanisms of IL18 in disease

K Yamanishi, M Hata, N Gamachi, Y Watanabe… - International Journal of …, 2023 - mdpi.com
Interleukin 18 (IL18) was originally identified as an inflammation-induced cytokine that is
secreted by immune cells. An increasing number of studies have focused on its non …

[HTML][HTML] LINC00958: A promising long non-coding RNA related to cancer

H Li, J Gao, L Liu, S Zhang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Long non-coding RNAs (lncRNAs), a class of RNA transcripts longer than 200 nucleotides,
do not encode proteins; however, they encode small peptides and micropeptides that act as …

[HTML][HTML] m6A-induced LINC00958 promotes breast cancer tumorigenesis via the miR-378a-3p/YY1 axis

D Rong, Q Dong, H Qu, X Deng, F Gao, Q Li… - Cell Death Discovery, 2021 - nature.com
Increasing evidence demonstrates that long noncoding RNAs (lncRNAs) play critical roles in
human breast cancer (BC) tumorigenesis. However, the mechanisms by which lncRNA and …

[HTML][HTML] linc00958/miR-185-5p/RSF-1 modulates cisplatin resistance and angiogenesis through AKT1/GSK3β/VEGFA pathway in cervical cancer

J Tian, L Cheng, E Kong, W Gu, Y Jiang, Q Hao… - Reproductive Biology …, 2022 - Springer
Background Chemoresistance is one of the major obstacles that lead to poor prognosis in
cervical cancer. linc00958 was reported to be an oncogene in cervical cancer. However, its …

[HTML][HTML] Development of siRNA-loaded lipid nanoparticles targeting long non-coding RNA LINC01257 as a novel and safe therapeutic approach for t (8; 21) pediatric …

P Connerty, E Moles, CE de Bock, N Jayatilleke… - Pharmaceutics, 2021 - mdpi.com
Standard of care therapies for children with acute myeloid leukemia (AML) cause potent off-
target toxicity to healthy cells, highlighting the need to develop new therapeutic approaches …

The regulation of long non-coding RNA 00958 (LINC00958) for oral squamous cell carcinoma (OSCC) cells death through absent in melanoma 2 (AIM2) depending …

L Jiang, W Ge, Y Cui, X Wang - Bioengineered, 2021 - Taylor & Francis
Long non-coding RNAs (lncRNAs) have been proposed as potential targets in OSCC gene
therapy. Thus, the study aims to analyze how they exert functions in OSCC. LINC00958 …

Long non-coding RNA LINC00511 regulates the expression of microRNA-625-5p and activates signal transducers and activators of transcription 3 (STAT3) to …

N Cui, Q Sun, H Liu, L Li, X Guo, Y Shi, C Jing… - …, 2021 - Taylor & Francis
This study aimed to investigate the expression, biological function, and downstream
mechanism of LINC00511 in gastric cancer (GC). In paired GC samples, LINC00511, miR …

[HTML][HTML] LINC00958 promotes bladder cancer carcinogenesis by targeting miR-490-3p and AURKA

H Zhen, P Du, Q Yi, X Tang, T Wang - Bmc Cancer, 2021 - Springer
Background Bladder cancer is a prevalent malignancy of the urinary system, in which long
non-coding RNAs (lncRNAs) are highly associated. We aimed to elucidate the role of …

[HTML][HTML] Longnon-coding RNA BLACAT2 promotes gastric cancer progression via the miR-193b-5p/METTL3 pathway

H Hu, Q Kong, X Huang, H Zhang, K Hu, Y Jing… - Journal of …, 2021 - ncbi.nlm.nih.gov
Gastric cancer is one of the leading prevalent and malignant cancers worldwide, especially
in east Asia. However, the in-depth molecular mechanism underlying gastric cancer …

[HTML][HTML] Long non‑coding RNA BLACAT2/miR‑378a‑3p/YY1 feedback loop promotes the proliferation, migration and invasion of uterine corpus endometrial carcinoma

C Zhang, R Wang, M Li, Q Yang - Oncology reports, 2023 - spandidos-publications.com
Uterine corpus endometrial carcinoma (UCEC) is a common gynecological malignancy with
high rates of mortality and morbidity. The expression of long non‑coding RNA bladder …