[HTML][HTML] Lupus and the lungs: the assessment and management of pulmonary manifestations of systemic lupus erythematosus

R Amarnani, SA Yeoh, EK Denneny, C Wincup - Frontiers in medicine, 2021 - frontiersin.org
Pulmonary manifestations of systemic lupus erythematosus (SLE) are wide-ranging and
debilitating in nature. Previous studies suggest that anywhere between 20 and 90% of …

Animal models to study cardiac arrhythmias

DJ Blackwell, J Schmeckpeper… - Circulation research, 2022 - Am Heart Assoc
Cardiac arrhythmias are a significant cause of morbidity and mortality worldwide, accounting
for 10% to 15% of all deaths. Although most arrhythmias are due to acquired heart disease …

Diagnosis and management of connective tissue disease‐associated interstitial lung disease in Australia and New Zealand: a position statement from the Thoracic …

AS Jee, R Sheehy, P Hopkins, TJ Corte… - …, 2021 - Wiley Online Library
Pulmonary complications in CTD are common and can involve the interstitium, airways,
pleura and pulmonary vasculature. ILD can occur in all CTD (CTD‐ILD), and may vary from …

Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases

M Acosta-Herrera, M Kerick… - Annals of the …, 2019 - ard.bmj.com
Objective Immune-mediated inflammatory diseases (IMIDs) are heterogeneous and complex
conditions with overlapping clinical symptoms and elevated familial aggregation, which …

[HTML][HTML] Systemic lupus erythematosus and pulmonary hypertension

K Parperis, N Velidakis, E Khattab… - International Journal of …, 2023 - mdpi.com
Pulmonary Hypertension (PH) is a common manifestation in patients with Systemic Lupus
Erythematosus (SLE) and varies from asymptomatic to life-threatening disease. PH can …

Conceptual framework for defining disease modification in systemic lupus erythematosus: a call for formal criteria

R van Vollenhoven, AD Askanase… - Lupus science & …, 2022 - lupus.bmj.com
Disease modification has become a well-established concept in several therapeutic areas;
however, no widely accepted definition of disease modification exists for SLE. We reviewed …

[HTML][HTML] Bacterial infections in lupus: Roles in promoting immune activation and in pathogenesis of the disease

M Battaglia, LA Garrett-Sinha - Journal of Translational Autoimmunity, 2021 - Elsevier
Background Bacterial infections of the lung, skin, bloodstream and other tissues are
common in patients with systemic lupus erythematosus (lupus) and are often more severe …

[HTML][HTML] Contribution of pulmonary function tests (PFTs) to the diagnosis and follow up of connective tissue diseases

N Ciancio, M Pavone, SE Torrisi, A Vancheri… - Multidisciplinary …, 2019 - Springer
Abstract Introduction Connective Tissue Diseases (CTDs) are systemic autoimmune
conditions characterized by frequent lung involvement. This usually takes the form of …

Pathological mechanisms of abnormal iron metabolism and mitochondrial dysfunction in systemic lupus erythematosus

C Wincup, N Sawford, A Rahman - Expert review of clinical …, 2021 - Taylor & Francis
Introduction: Systemic lupus erythematosus [SLE] is a chronic, autoimmune condition
characterized by the formation of autoantibodies directed against nuclear components and …

Impact of belimumab on organ damage in systemic lupus erythematosus

MB Urowitz, C Aranow, Y Asukai… - Arthritis Care & …, 2022 - Wiley Online Library
Organ damage is a key determinant of poor long‐term prognosis and early death in patients
with systemic lupus erythematosus (SLE). Prevention of damage is a key treatment goal of …