Introduction Multiple sclerosis (MS) is a chronic autoimmune disorder that affects the central
nervous system and compromises the health and well-being of millions of people worldwide …

Multiple sclerosis (MS) and its animal model of experimental autoimmune encephalomyelitis
(EAE) are characterized by focal inflammatory infiltrates into the central nervous system …

Aims Multiple sclerosis (MS) is a progressive inflammatory neurological disease affecting
myelin, neurons and glia. Demyelination and neurodegeneration of cortical grey matter …

The contribution of vitamin D insufficiency to the pathogenesis of multiple sclerosis (MS) is
reviewed. Among the multiple recently discovered actions of vitamin D, an …

Multiple sclerosis (MS) is a debilitating disease characterized by demyelination of the central
nervous system (CNS), resulting in widespread formation of white matter lesions (WMLs) …

Multiple sclerosis is caused by a complex interaction between genetic predisposition and
environmental factors. Epstein–Barr virus (EBV) is an environmental risk factor that is …

Teriflunomide is an inhibitor of dihydro-orotate dehydrogenase (DHODH), and is
hypothesized to ameliorate multiple sclerosis by reducing proliferation of stimulated …

Background and Objectives Follicular helper T (Tfh) cells play a critical role in protective
immunity helping B cells produce antibodies against foreign pathogens and are likely …

Radiologically Isolated Syndrome (RIS) is characterized by MRI-typical brain lesions
fulfilling the 2009 Okuda criteria, detected in patients without clinical conditions suggestive …

The etiology of multiple sclerosis (MS) is still unclear. The immuno-pathogenic phenomena
leading to neurodegeneration are thought to be triggered by environmental (viral?) factors …