Vitamin D as an immune modulator in multiple sclerosis

H Bartosik-Psujek, M Psujek - Neurologia i neurochirurgia …, 2019 - journals.viamedica.pl
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disorder of the
central nervous system. The disease is characterised by inflammation with extensive …

Treating multiple sclerosis with monoclonal antibodies: a 2013 update

A Deiß, I Brecht, A Haarmann… - Expert review of …, 2013 - Taylor & Francis
The third part of this in-depth review series on the treatment of multiple sclerosis (MS) with
monoclonal antibodies covers the years 2010–2012. The natalizumab section gives a …

Towards a comprehensive etiopathogenetic and pathophysiological theory of multiple sclerosis

TO Tobore - International journal of neuroscience, 2020 - Taylor & Francis
Background: Multiple sclerosis (MS) is a neurodegenerative disease caused by dysfunction
of the immune system that affects the central nervous system (CNS). It is characterized by …

Current perspectives: evidence to date on BTK inhibitors in the management of multiple sclerosis

E Carnero Contentti, J Correale - Drug Design, Development and …, 2022 - Taylor & Francis
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
leading to demyelination and neurodegeneration. Basic and translational studies have …

Role of prolactin in B cell regulation in multiple sclerosis

J Correale, MF Farez, MC Ysrraelit - Journal of Neuroimmunology, 2014 - Elsevier
The role of prolactin in MS pathogenesis was investigated. Prolactin levels were higher in
MS subjects both during remission and exacerbation compared to control subjects. Prolactin …

CXCL10 and CXCL13 chemokines in patients with relapsing remitting and primary progressive multiple sclerosis

P Iwanowski, J Losy, L Kramer, M Wójcicka… - Journal of the …, 2017 - Elsevier
Objectives Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system characterized by a variable clinical course. Different pathogenic …

Impact of glatiramer acetate on B cell-mediated pathogenesis of multiple sclerosis

S Kuerten, LJ Jackson, J Kaye, TL Vollmer - CNS drugs, 2018 - Springer
Growing evidence indicates that B cells play a key role in the pathogenesis of multiple
sclerosis (MS). B cells occupy distinct central nervous system (CNS) compartments in MS …

Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients

JR Rivas, SJ Ireland, R Chkheidze, WH Rounds… - Acta …, 2017 - Springer
Plasmablasts are a highly differentiated, antibody secreting B cell subset whose prevalence
correlates with disease activity in Multiple Sclerosis (MS). For most patients experiencing …

Human mesenchymal stem cells upregulate CD1dhighCD5+ regulatory B cells in experimental autoimmune encephalomyelitis

Y Guo, KH Chan, WH Lai, CW Siu, SC Kwan… - …, 2013 - karger.com
Background/Aims: Multiple sclerosis (MS) causes significant neurological disability.
Experimental autoimmune encephalomyelitis (EAE) is an animal model of MS. Human bone …

Human interferon regulatory factor 5 homologous epitopes of Epstein-Barr virus and Mycobacterium avium subsp. paratuberculosis induce a specific humoral and …

D Cossu, G Mameli, G Galleri, E Cocco… - Multiple sclerosis …, 2015 - journals.sagepub.com
Background: A large number of reports indicate the association of Epstein-Barr virus (EBV),
and Mycobacterium avium subsp. paratuberculosis (MAP) with multiple sclerosis (MS) …