Introduction: MicroRNAs (miRNAs) are an emerging group of small noncoding RNAs that
regulate gene expression posttranscriptionally, by targeting messenger RNAs (mRNAs) for …

Heavy neurofilaments (NFH) released from neurons during axonal injury induce a humoral
immune response. We measured CSF and serum levels of NFH proteins and anti-NFH IgG …

Background: Advanced glycation end products (AGEs) are involved in the pathogenesis of
many diseases, including neurodegenerative diseases such as multiple sclerosis (MS). The …

Background Multiple sclerosis (MS) is a CNS inflammatory demyelinating disorder. T helper
1 (Th1) and T helper 17 (Th17) cells are important in MS immunopathogenesis. Level of …

Objectives Epstein–Barr virus (EBV) infection is associated with multiple sclerosis (MS), and
EBV may transform lymphoblastoid cell lines more frequently in MS patients than controls …

Apolipoprotein D (Apo D) is a key molecule in the lipid transport during homeostasis and
repair processes in normal and pathological conditions of the nervous system with a putative …

The effects of interferon-beta (IFN-β), one of the key immunotherapies used in multiple
sclerosis (MS), on peripheral blood leukocytes and T cells have been extensively studied. B …

Multiple sclerosis (MS) is a chronic demyelinating inflammatory disease of the central
nervous system (CNS) affecting prevalently young adults (1, 2). The pathogenesis of MS has …

Multiple sclerosis (MS) is an immune‐mediated demyelinating disorder of unknown etiology.
Both genetic‐susceptibility and environment exposures, including vitamin D deficiency …

Cuprizone, copper chelator, treatment of mouse is a toxic model of multiple sclerosis (MS) in
which oligodendrocyte death, demyelination and remyelination can be observed …