Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
The coronavirus disease-19 pandemic (COVID-19), which appeared in China in December
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …
2019 and rapidly spread throughout the world, has forced clinicians and scientists to take up …
[HTML][HTML] Systematic review of safety and efficacy of IL-1-targeted biologics in treating immune-mediated disorders
DD Arnold, A Yalamanoglu, O Boyman - Frontiers in Immunology, 2022 - frontiersin.org
Background The cytokine interleukin (IL)-1 plays a pivotal role in immune-mediated
disorders, particularly in autoinflammatory diseases. Targeting this cytokine proved to be …
disorders, particularly in autoinflammatory diseases. Targeting this cytokine proved to be …
[HTML][HTML] Canakinumab for the treatment of autoinflammatory recurrent fever syndromes
Abstract Background Familial Mediterranean fever, mevalonate kinase deficiency (also
known as the hyperimmunoglobulinemia D syndrome), and the tumor necrosis factor …
known as the hyperimmunoglobulinemia D syndrome), and the tumor necrosis factor …
[HTML][HTML] Controlling cytokine storm is vital in COVID-19
L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
Corona virus disease 2019 (COVID-19) has caused a global outbreak and severely posed
threat to people's health and social stability. Mounting evidence suggests that …
threat to people's health and social stability. Mounting evidence suggests that …
Familial Mediterranean fever, from pathogenesis to treatment: a contemporary review
A Tufan, H LACHMANN - Turkish Journal of Medical …, 2020 - journals.tubitak.gov.tr
Abstract Familial Mediterranean fever (FMF)(OMIM# 249100) is the most common hereditary
autoinflammatory disease in the world. FMF is caused by gain of function mutations of MEFV …
autoinflammatory disease in the world. FMF is caused by gain of function mutations of MEFV …
Role of inflammasomes in the pathogenesis of periodontal disease and therapeutics
JT Marchesan, MS Girnary, K Moss… - Periodontology …, 2020 - Wiley Online Library
Inflammasomes are a group of multimolecular intracellular complexes assembled around
several innate immune proteins. Recognition of a diverse range of microbial, stress and …
several innate immune proteins. Recognition of a diverse range of microbial, stress and …
Inflammatory osteolysis: a conspiracy against bone
There are many causes of inflammatory osteolysis, but regardless of etiology and cellular
contexts, the osteoclast is the bone-degrading cell. Thus, the impact of inflammatory …
contexts, the osteoclast is the bone-degrading cell. Thus, the impact of inflammatory …
Familial Mediterranean fever, review of the literature
M Alghamdi - Clinical rheumatology, 2017 - Springer
Familial Mediterranean fever (FMF) is the most common monogenic periodic fever syndrome
and characterized by recurrent episodes of fever, serositis, arthritis, dermal manifestations …
and characterized by recurrent episodes of fever, serositis, arthritis, dermal manifestations …
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean …
F Moghaddas, R Llamas, D De Nardo… - Annals of the …, 2017 - ard.bmj.com
Objective Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis (PAAND) is a
recently described monogenic autoinflammatory disease. The causal p. S242R MEFV …
recently described monogenic autoinflammatory disease. The causal p. S242R MEFV …
Familial mediterranean fever
H Ozdogan, S Ugurlu - La Presse Médicale, 2019 - Elsevier
Summary Familial Mediterranean Fever (FMF) is the oldest and the most frequent of all
described hereditary periodic fever syndromes. The populations originating from …
described hereditary periodic fever syndromes. The populations originating from …