The flavonoid silymarin extracted from the seeds of Sylibum marianum is a mixture of 6
flavolignan isomers. The 3 more important isomers are silybin (or silibinin), silydianin, and …

Melittin, a main component of bee venom, is a cationic amphiphilic peptide with a linear α-
helix structure. It has been reported that melittin can exert pharmacological effects, such as …

Simple Summary Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor
prognosis. The lack of early diagnosis and the absence of suitable biomarkers coupled with …

Melittin is a promising antitumor substance; however, it is a nonspecific cytolytic peptide,
which limits its clinical application. In this study, melittin liposomes (Mel-Lip) and hyaluronic …

Tumors pose a great threat to human health; as a subgroup of tumor cells, cancer stem cells
(CSCs) contribute to the genesis, development, metastasis, and recurrence of tumors …

Background Pancreatic ductal adenocarcinoma (PDAC) is a malignancy with a 5-year
survival rate of 12%. The abundant mesenchyme is partly responsible for the malignancy …

Pancreatic cancer is the seventh leading cause of cancer-related deaths, and chemotherapy
is one of the most important treatments for pancreatic cancer. Unfortunately, pancreatic …

Various therapeutic approaches are conducted for regression of liver fibrosis and prevent
possible further carcinogenic transformation. This study was aimed to assess the …

Background: Exosomes play a role in intercellular communication and participate in the
interaction between pancreatic ductal adenocarcinoma (PDAC) cells and immune cells …

The idea to propose this ambitious title for a Special Issue in the International Journal of
Molecular Science came, on one hand, from my personal experience in research in …