The liver is an important immunological organ that controls systemic tolerance. The liver
harbors professional and unconventional antigen-presenting cells that are crucial for …

One of the hallmarks of cancer is the ability to activate invasion and metastasis. Cancer
morbidity and mortality are largely related to the spread of the primary, localized tumour to …

A case of a young girl diagnosed with an antibody deficiency syndrome serves to highlight
the role of CD81 in B cell biology. Moreover, this case illustrates a fundamental function of …

Optimal T cell activation requires Ag recognition through the TCR, engagement of
costimulatory molecules, and cytokines. T cells can also directly recognize danger signals …

In this study, we investigated the dynamics of the molecular interactions of tetraspanin CD81
in T lymphocytes, and we show that CD81 controls the organization of the immune synapse …

Aim This cross‐sectional case–control study was designed to determine the association of
the salivary concentration of CD 9/CD 81 exosome‐related tetraspanins with the periodontal …

CD81 participates in a variety of important cellular processes such as membrane
organization, protein trafficking, cellular fusion and cell–cell interactions. In the immune …

The disturbance of maternal immune tolerance to a semiallogeneic fetus is recognized as
one of the key pathologies of preeclampsia (PE), in which an imbalance between the …

Latently infected resting CD4+ T cells are a major barrier to HIV cure. Understanding how
latency is established, maintained and reversed is critical to identifying novel strategies to …

Tetraspanin-enriched microdomains (TEMs) are specialized membrane platforms driven by
protein–protein interactions that integrate membrane receptors and adhesion molecules …