The liver cancer immune microenvironment: Therapeutic implications for hepatocellular carcinoma

R Donne, A Lujambio - Hepatology, 2023 - journals.lww.com
The liver is the sixth most common site of primary cancer in humans and the fourth leading
cause of cancer‐related death in the world. Hepatocellular carcinoma (HCC) accounts for …

Prognostic role of neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR) and lymphocyte-to-C reactive protein …

R Minici, MA Siciliano, M Ammendola, RC Santoro… - Cancers, 2022 - mdpi.com
Simple Summary Response to TACE is a surrogate marker of tumor aggressive biology, with
manifold practical implications. In turn, inflammation-based scores are biomarkers of the …

Efficacy and safety of lenvatinib combined with PD-1 inhibitors plus TACE for unresectable hepatocellular carcinoma patients in China real-world

X Li, Z Fu, X Chen, K Cao, J Zhong, L Liu… - Frontiers in …, 2022 - frontiersin.org
Purpose To evaluate the efficacy and safety of lenvatinib combined with programmed death
receptor-1 signaling inhibitors plus transarterial chemoembolization (LePD1-TACE) for …

Predictive biomarkers of survival in patients with advanced hepatocellular carcinoma receiving atezolizumab plus bevacizumab treatment

YE Chon, J Cheon, H Kim, B Kang, Y Ha… - Cancer …, 2023 - Wiley Online Library
Background Since atezolizumab plus bevacizumab (ATE+ BEV) regimen for patients with
unresectable hepatocellular carcinoma (HCC) was released quite recently, real‐world data …

Usefulness of neutrophil‐to‐lymphocyte ratio in predicting progression and survival outcomes after atezolizumab–bevacizumab treatment for hepatocellular …

H Ochi, M Kurosaki, K Joko, T Mashiba… - Hepatology …, 2023 - Wiley Online Library
Aim We investigated pretreatment neutrophil‐to‐lymphocyte ratio (NLR) for predicting
survival outcomes of atezolizumab plus bevacizumab therapy for hepatocellular carcinoma …

The monocyte to lymphocyte ratio not only at baseline but also at relapse predicts poor outcomes in patients with hepatocellular carcinoma receiving locoregional …

Q Wang, W Qiao, B Liu, J Li, C Yuan, J Long, C Hu… - BMC …, 2022 - Springer
Background Monocyte to lymphocyte ratio (MLR) represents a pro-inflammatory immune
microenvironment. The aim of this study was to elucidate the effect of MLR and subsequent …

Local and regional therapies for hepatocellular carcinoma and future combinations

A Hatzidakis, L Müller, M Krokidis, R Kloeckner - Cancers, 2022 - mdpi.com
Simple Summary Percutaneous interventional radiological techniques offer many
alternatives for treatment of Hepatocellular Carcinoma (HCC) using local anesthesia and …

Pretreatment neutrophil-to-lymphocyte ratio associated with tumor recurrence and survival in patients achieving a pathological complete response following …

CM Huang, MY Huang, HL Tsai, CW Huang, WC Su… - Cancers, 2021 - mdpi.com
Simple Summary Patients with locally advanced rectal cancer who achieve a pathological
complete response to neoadjuvant chemoradiotherapy have been associated with excellent …

Intermediate-stage (BCLC stage B) infiltrative hepatocellular carcinoma: safety and efficacy of chemoembolization

SH Kim, JH Kim, GH Kim, JH Kim, HK Ko, HH Chu… - European …, 2023 - Springer
Objectives To evaluate the safety and efficacy of chemoembolization in patients with
intermediate-stage infiltrative Hepatocellular carcinoma (HCC). Materials and methods This …

[HTML][HTML] Adding nutritional status to the original BCLC stage improves mortality prediction for hepatocellular carcinoma patients in HBV-endemic regions

YT Lin, PT Lin, CC Lin, TH Wu, LT Liu… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is associated with high mortality, especially in Asian
populations where chronic HBV infection is a major cause. Accurate prediction of mortality …