Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …

The monoamine hypothesis has been accepted as the most common hypothesis of major
depressive disorder (MDD) for a long period because of its simplicity and understandability …

In the adult hippocampus, neuroprogenitor cells in the subgranular zone (SGZ) of the
dentate gyrus give rise to newborn neuroblasts. However, only a small subset of these cells …

Background Essentially all knowledge about adult hippocampal neurogenesis in humans
still comes from one seminal study by Eriksson et al. in 1998, although several others have …

The adult brain is a plastic place. To ensure that the mature nervous system's control of
behaviour is flexible in the face of a varying environment, morphological and physiological …

Alzheimer's disease (AD) is neurodegenerative disorder that is associated with memory and
cognitive decline in the older adults. Scopolamine is commonly used as a behavioral model …

The P7C3 class of aminopropyl carbazole chemicals fosters the survival of neurons in a
variety of rodent models of neurodegeneration or nerve cell injury. To uncover its …

An in vivo screen was performed in search of chemicals capable of enhancing neuron
formation in the hippocampus of adult mice. Eight of 1000 small molecules tested enhanced …

New neurons are generated in the adult hippocampus of many species including rodents,
monkeys, and humans. Conditions associated with major depression, such as social stress …