Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …
mammalian brain into adulthood. Adult neurogenesis has been best described in the …
Neurogenesis in the adult hippocampus
G Kempermann, H Song… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Of the neurogenic zones in the adult brain, adult hippocampal neurogenesis attracts the
most attention, because it is involved in higher cognitive function, most notably memory …
most attention, because it is involved in higher cognitive function, most notably memory …
Neural basis of major depressive disorder: Beyond monoamine hypothesis
The monoamine hypothesis has been accepted as the most common hypothesis of major
depressive disorder (MDD) for a long period because of its simplicity and understandability …
depressive disorder (MDD) for a long period because of its simplicity and understandability …
[HTML][HTML] Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis
A Sierra, JM Encinas, JJP Deudero, JH Chancey… - Cell stem cell, 2010 - cell.com
In the adult hippocampus, neuroprogenitor cells in the subgranular zone (SGZ) of the
dentate gyrus give rise to newborn neuroblasts. However, only a small subset of these cells …
dentate gyrus give rise to newborn neuroblasts. However, only a small subset of these cells …
Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years
R Knoth, I Singec, M Ditter, G Pantazis, P Capetian… - PloS one, 2010 - journals.plos.org
Background Essentially all knowledge about adult hippocampal neurogenesis in humans
still comes from one seminal study by Eriksson et al. in 1998, although several others have …
still comes from one seminal study by Eriksson et al. in 1998, although several others have …
Adult neurogenesis and functional plasticity in neuronal circuits
The adult brain is a plastic place. To ensure that the mature nervous system's control of
behaviour is flexible in the face of a varying environment, morphological and physiological …
behaviour is flexible in the face of a varying environment, morphological and physiological …
The cellular and molecular processes associated with scopolamine-induced memory deficit: A model of Alzheimer's biomarkers
K San Tang - Life sciences, 2019 - Elsevier
Alzheimer's disease (AD) is neurodegenerative disorder that is associated with memory and
cognitive decline in the older adults. Scopolamine is commonly used as a behavioral model …
cognitive decline in the older adults. Scopolamine is commonly used as a behavioral model …
P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage
G Wang, T Han, D Nijhawan, P Theodoropoulos… - Cell, 2014 - cell.com
The P7C3 class of aminopropyl carbazole chemicals fosters the survival of neurons in a
variety of rodent models of neurodegeneration or nerve cell injury. To uncover its …
variety of rodent models of neurodegeneration or nerve cell injury. To uncover its …
Discovery of a proneurogenic, neuroprotective chemical
AA Pieper, S Xie, E Capota, SJ Estill, J Zhong, JM Long… - Cell, 2010 - cell.com
An in vivo screen was performed in search of chemicals capable of enhancing neuron
formation in the hippocampus of adult mice. Eight of 1000 small molecules tested enhanced …
formation in the hippocampus of adult mice. Eight of 1000 small molecules tested enhanced …
Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates
TD Perera, JD Coplan, SH Lisanby… - Journal of …, 2007 - Soc Neuroscience
New neurons are generated in the adult hippocampus of many species including rodents,
monkeys, and humans. Conditions associated with major depression, such as social stress …
monkeys, and humans. Conditions associated with major depression, such as social stress …