Airway-on-a-chip: designs and applications for lung repair and disease

TJ Bennet, A Randhawa, J Hua, KC Cheung - Cells, 2021 - mdpi.com
The lungs are affected by illnesses including asthma, chronic obstructive pulmonary
disease, and infections such as influenza and SARS-CoV-2. Physiologically relevant models …

Nebulized therapies in COPD: past, present, and the future

IZ Barjaktarevic, AP Milstone - International journal of chronic …, 2020 - Taylor & Francis
Current guidelines recommend inhalation therapy as the preferred route of drug
administration for treating patients with chronic obstructive pulmonary disease (COPD) …

Small airways diseases, excluding asthma and COPD: an overview

PR Burgel, A Bergeron, J de Blic… - European respiratory …, 2013 - Eur Respiratory Soc
This review is the summary of a workshop on small airways disease, which took place in
Porquerolles, France in November 2011. The purpose of this workshop was to review the …

The role of the small airways in the pathophysiology of asthma and chronic obstructive pulmonary disease

M Bonini, OS Usmani - Therapeutic Advances in Respiratory …, 2015 - journals.sagepub.com
Chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease
(COPD), represent a major social and economic burden for worldwide health systems …

[HTML][HTML] Gut-lung crosstalk in pulmonary involvement with inflammatory bowel diseases

H Wang, JS Liu, SH Peng, XY Deng… - World Journal of …, 2013 - ncbi.nlm.nih.gov
Pulmonary abnormalities, dysfunction or hyper-reactivity occurs in association with
inflammatory bowel disease (IBD) more frequently than previously recognized. Emerging …

Lipid-based pulmonary delivery system: a review and future considerations of formulation strategies and limitations

CL Ngan, AA Asmawi - Drug delivery and translational research, 2018 - Springer
Inhalation therapy of lipid-based carriers has great potential in direct target towards the root
of respiratory diseases, which make them superior over other drug deliveries. With the …

Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association-GAA) and …

F Braido, N Scichilone, F Lavorini, OS Usmani… - World Allergy …, 2016 - Springer
Evidence that enables us to identify, assess, and access the small airways in asthma and
chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma …

Association between emphysema-like lung on cardiac computed tomography and mortality in persons without airflow obstruction: a cohort study

EC Oelsner, EA Hoffman, AR Folsom… - Annals of internal …, 2014 - acpjournals.org
Background: Low lung function is known to predict mortality in the general population, but
the prognostic significance of emphysema on computed tomography (CT) in persons without …

[HTML][HTML] Validation of human small airway measurements using endobronchial optical coherence tomography

Y Chen, M Ding, W Guan, W Wang, W Luo, C Zhong… - Respiratory …, 2015 - Elsevier
Background Small airway remodeling is the cardinal feature underlying chronic airway
diseases. There is no modality which identifies small airway pathological changes, which is …

Inhaled dual phosphodiesterase 3/4 inhibitors for the treatment of patients with COPD: a short review

C Martin, PR Burgel, N Roche - International Journal of Chronic …, 2021 - Taylor & Francis
Current pharmacological treatments for chronic obstructive pulmonary disease (COPD) are
mostly limited to inhaled bronchodilators and corticosteroids. Azithromycin can contribute to …