Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging

PJ Gawne, F Man, PJ Blower… - Chemical reviews, 2022 - ACS Publications
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …

Clinical applications of Gallium-68

SR Banerjee, MG Pomper - Applied Radiation and Isotopes, 2013 - Elsevier
Gallium-68 is a positron-emitting radioisotope that is produced from a 68Ge/68Ga generator.
As such it is conveniently used, decoupling radiopharmacies from the need for a cyclotron …

Mechanisms of therapeutic activity for gallium

LR Bernstein - Pharmacological reviews, 1998 - ASPET
Gallium, a semi-metallic element in group 13 (IIIa) of the periodic table, has shown efficacy
in the treatment of several apparently diverse disorders. These disorders can be broadly …

Antitumour metal compounds: more than theme and variations

MA Jakupec, MS Galanski, VB Arion, CG Hartinger… - Dalton …, 2008 - pubs.rsc.org
Triggered by the resounding success of cisplatin, the past decades have seen tremendous
efforts to produce clinically beneficial analogues. The recent achievement of oxaliplatin for …

Technetium and gallium derived radiopharmaceuticals: comparing and contrasting the chemistry of two important radiometals for the molecular imaging era

MD Bartholoma, AS Louie, JF Valliant… - Chemical …, 2010 - ACS Publications
The objective of medical imaging using molecular probes and perfusion radiotracers is to
provide rapid, noninvasive evaluation of physiology, pathology, and/or organ function. The …

Coordination compounds in nuclear medicine

S Jurisson, D Berning, W Jia, D Ma - Chemical reviews, 1993 - ACS Publications
Radiopharmaceuticals, drugs containing a radionu-clide, are used routinely in nuclear
medicine depart-ments for the diagnosis of disease and are under investigation for use in …

Metals and metal compounds in cancer treatment

B Desoize - Anticancer Research, 2004 - ar.iiarjournals.org
Metals and metal compounds have been used in medicine for several thousands of years. In
this review we summarized the anti-cancer activities of the ten most active metals: arsenic …

68Ga‐PET: a powerful generator‐based alternative to cyclotron‐based PET radiopharmaceuticals

M Fani, JP André, HR Maecke - Contrast media & molecular …, 2008 - Wiley Online Library
PET (positron emission tomography) is a powerful diagnostic and imaging technique which
requires short‐lived positron emitting isotopes. The most commonly used are accelerator …

Radiolabelling DOTA-peptides with 68Ga

WAP Breeman, M de Jong, E de Blois… - European journal of …, 2005 - Springer
Purpose A new field of interest is the application of 68 Ga-labelled DOTA-conjugated
peptides for positron emission tomography (PET). The commercially available or house …

68Ga-labeled peptides in tumor imaging

HR Maecke, M Hofmann… - Journal of Nuclear …, 2005 - Soc Nuclear Med
Radiolabeled peptides are of increasing interest in nuclear oncology. Special emphasis has
been given to the development of peptides labeled with positron emitters. Among these, 68 …