The occurrence of drug-resistant bacterial infections impulses the development of new
antibacterial agents that own a mechanism of action different from traditional antibiotics …

Hypoxia-inducible factors (HIFs) are transcription factors that are expressed in the hypoxic
tumor microenvironment. They are involved in the cellular adaptations by improving the …

Aim Deformity in the cellular homeostatic event associated with cell survival and apoptosis
are committing factors for carcinogenesis. Interventions of these events by …

Ascites malignancy is a frequent cause of morbidity and presents significant management
problems which occur in many cancers. Angiogenesis plays a major role in the prognosis of …

Purpose The declined oxygen tension in the cancer cell leads to the hypoxic adaptive
response and favors establishment of tumor micro environment [TEM]. The complex TME …

A previous study for the identification of acetylcholinesterase (AChE) inhibitors
demonstrated that the hybrid between tyrosol, the 1, 2, 3-triazole nucleus, and the coumarin …

Curcumin (diferuloylmethane) is bioactive phenolic compound which exerts diverse
antimetastatic effect. Several studies have reported the antimetastatic effect of curcumin by …

Reigning of the abnormal gene activation associated with survival signalling in lung cancer
leads to the anomalous growth and therapeutic failure. Targeting specific cell survival …

Disrupted redox balance is implicated in multiple pathologies including malignant
progression and tumor angiogenesis. In this investigation, we report the design and …

In modern biology, one of the major topics of importance is progress in anti-cancer drugs
with specific targets. The angiopreventive and in vitro tumor inhibition activities of novel …