[HTML][HTML] Myelin fat facts: an overview of lipids and fatty acid metabolism

Y Poitelon, AM Kopec, S Belin - Cells, 2020 - mdpi.com
Myelin is critical for the proper function of the nervous system and one of the most complex
cell–cell interactions of the body. Myelination allows for the rapid conduction of action …

[HTML][HTML] Evolution of blood–brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies

L Han, C Jiang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Blood–brain barrier (BBB) strictly controls matter exchange between blood and brain, and
severely limits brain penetration of systemically administered drugs, resulting in ineffective …

[HTML][HTML] Effects of dietary fatty acids in pancreatic beta cell metabolism, implications in homeostasis

P Acosta-Montaño, V García-González - Nutrients, 2018 - mdpi.com
Fatty acids are involved in several metabolic processes, including the development of
metabolic and cardiovascular diseases. In recent years a disease that has received …

[HTML][HTML] CD36 in Alzheimer's disease: an overview of molecular mechanisms and therapeutic targeting

AM Dobri, M Dudău, AM Enciu, ME Hinescu - Neuroscience, 2021 - Elsevier
CD36 is a membrane protein with wide distribution in the human body, is enriched in the
monocyte-macrophage system and endothelial cells, and is involved in the cellular uptake of …

Association of red blood cell omega-3 fatty acids with MRI markers and cognitive function in midlife: the framingham heart study

CL Satizabal, JJ Himali, AS Beiser, V Ramachandran… - Neurology, 2022 - AAN Enterprises
Background and Objectives Diet may be a key contributor to brain health in midlife. In
particular, omega-3 fatty acids have been related to better neurologic outcomes in older …

[HTML][HTML] Punicic acid and its role in the prevention of neurological disorders: A review

CM Guerra-Vázquez, M Martínez-Ávila… - Foods, 2022 - mdpi.com
Millions of people worldwide are affected by neurodegenerative diseases (NDs). NDs are
characterized by progressive damage and death of nerve cells accompanied by high levels …

[HTML][HTML] Marine biocompounds for neuroprotection—A review

AF Bălașa, C Chircov, AM Grumezescu - Marine Drugs, 2020 - mdpi.com
While terrestrial organisms are the primary source of natural products, recent years have
witnessed a considerable shift towards marine-sourced biocompounds. They have achieved …

Astrocyte-derived fatty acid-binding protein 7 protects blood-brain barrier integrity through a caveolin-1/MMP signaling pathway following traumatic brain injury

Q Rui, H Ni, X Lin, X Zhu, D Li, H Liu, G Chen - Experimental neurology, 2019 - Elsevier
The astrocyte-endothelial cell interaction is crucial for normal brain homeostasis and blood-
brain barrier (BBB) disruption in pathological conditions. However, the mechanism by which …

[HTML][HTML] FABP5 regulates the proliferation of clear cell renal cell carcinoma cells via the PI3K/AKT signaling pathway

Q Lv, G Wang, Y Zhang, X Han… - International …, 2019 - spandidos-publications.com
Clear cell renal cell carcinoma (ccRCC) has been associated with one of the highest
mortality rates among all cancers. Fatty acid binding proteins (FABPs) are 14‑15 kDa …

[HTML][HTML] Advancement of epigenetics in stroke

J Peng, D Ghosh, F Zhang, L Yang, J Wu… - Frontiers in …, 2022 - frontiersin.org
A wide plethora of intervention procedures, tissue plasminogen activators, mechanical
thrombectomy, and several neuroprotective drugs were reported in stroke research over the …