Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

Sperm DNA integrity is crucial for fertilization and development of healthy offspring. The
spermatozoon undergoes extensive molecular remodeling of its nucleus during later phases …

Infertility is a prevalent condition affecting an estimated 70 million people globally. The
World Health Organization estimates that 9% of couples worldwide struggle with fertility …

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for
male fertility evaluation. While its detrimental implications on sperm function were …

Intracytoplasmic sperm injection (ICSI) has become the most commonly used method of
fertilization in assisted reproductive technology. The primary reasons for its popularity stem …

Varicocele has been associated with reduced male reproductive potential. With the
advances in biomolecular techniques, it has been possible to better understand the …

STUDY QUESTION Does microfluidic sorting improve the selection of sperm with lower DNA
fragmentation over standard density-gradient centrifugation? SUMMARY ANSWER …

Objective To compare sperm DNA fragmentation (SDF) levels between testicular and
ejaculated sperm and to evaluate outcomes of intracytoplasmic sperm injection (ICSI) with …

Studies have explored the influence of DNA damage in assisted reproductive technology
(ART), but the outcome remains controversial. To determine whether sperm DNA …