Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …

Pulmonary fibrosis is a chronic, progressive, incurable interstitial lung disease with high
mortality after diagnosis and remains a global public health problem. Despite advances and …

The pathogenesis of lung fibrosis involves hyperactivation of innate and adaptive immune
pathways that release inflammatory cytokines and growth factors such as tumor growth …

Background Idiopathic pulmonary fibrosis (IPF) is fibrotic lung disease with no effective
treatment. It is characterized by destruction of alveolar structure and pulmonary interstitial …

Pulmonary fibrosis (PF) is the pathological change of end-stage interstitial lung diseases
with high mortality and limited therapeutic options. Lung macrophages have distinct subsets …

Pulmonary fibrosis (PF) is a serious and often fatal illness that occurs in various clinical
settings and represents a significant unmet medical need. Increasing evidence indicates that …

Idiopathic pulmonary fibrosis (IPF), characterized by progressive worsening of dyspnea and
irreversible decline in lung function, is a chronic and progressive respiratory disease with a …

Idiopathic pulmonary fibrosis is a chronic disease characterized by progressive lung
scarring that inhibits gas exchange. Evidence suggests fibroblast-matrix interactions are a …

Bacterial or viral infections, such as Brucella, mumps virus, herpes simplex virus, and Zika
virus, destroy immune homeostasis of the testes, leading to spermatogenesis disorder and …

Alveolar macrophages (AMs) are specialized tissue-resident macrophages that orchestrate
the immune response in allergic inflammation and asthma. However, what signals direct …