Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies

S Paul, E Candelario-Jalil - Experimental neurology, 2021 - Elsevier
Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

Biomaterial-supported MSC transplantation enhances cell–cell communication for spinal cord injury

B Lv, X Zhang, J Yuan, Y Chen, H Ding, X Cao… - Stem Cell Research & …, 2021 - Springer
The spinal cord is part of the central nervous system (CNS) and serves to connect the brain
to the peripheral nervous system and peripheral tissues. The cell types that primarily …

Effect of remote ischemic conditioning vs usual care on neurologic function in patients with acute moderate ischemic stroke: the RICAMIS randomized clinical trial

HS Chen, Y Cui, XQ Li, XH Wang, YT Ma, Y Zhao… - Jama, 2022 - jamanetwork.com
Importance Preclinical and clinical studies have suggested a neuroprotective effect of
remote ischemic conditioning (RIC), which involves repeated occlusion/release cycles on …

Safety and efficacy of remote ischemic postconditioning after thrombolysis in patients with stroke

J An, Y Cheng, Y Guo, M Wei, M Gong, Y Tang… - Neurology, 2020 - AAN Enterprises
Objective To determine the effect of remote ischemic postconditioning (RIPC) on patients
with acute ischemic stroke (AIS) undergoing IV thrombolysis (IVT). Methods A single-center …

The effect of repeated remote ischemic postconditioning after an ischemic stroke (REPOST): A randomized controlled trial

TRJ Landman, Y Schoon, MC Warlé… - … Journal of Stroke, 2023 - journals.sagepub.com
Background and Aims: A potential strategy to treat ischemic stroke may be the application of
repeated remote ischemic postconditioning (rIPostC). This consists of several cycles of brief …

Immunomodulatory therapeutic strategies in stroke

K Malone, S Amu, AC Moore, C Waeber - Frontiers in pharmacology, 2019 - frontiersin.org
The role of immunity in all stages of stroke is increasingly being recognized, from the
pathogenesis of risk factors to tissue repair, leading to the investigation of a range of …

Time from onset to remote ischemic conditioning and clinical outcome after acute moderate ischemic stroke

Y Cui, YN Chen, TN Nguyen, HS Chen - Annals of Neurology, 2023 - Wiley Online Library
Objective We conducted a post hoc exploratory analysis of Remote Ischemic Conditioning
for Acute Moderate Ischemic Stroke (RICAMIS) to determine whether early remote ischemic …

Remote ischemic conditioning as an additional treatment for acute ischemic stroke: the preclinical and clinical evidence

TRJ Landman, Y Schoon, MC Warlé, FE de Leeuw… - Stroke, 2019 - Am Heart Assoc
Methods A formal systematic review was not performed because of the heterogeneity of the
studies and recently published systematic reviews on preclinical 12 and clinical studies. 13 …

Remote ischemic conditioning for stroke: A critical systematic review

H Keevil, BE Phillips… - International Journal of …, 2024 - journals.sagepub.com
Remote ischemic conditioning (RIC) is the application of brief periods of ischemia to an
organ or tissue with the aim of inducing protection from ischemia in a distant organ. It was …

Effects of ischemic postconditioning and long non-coding RNAs in ischemic stroke

W Ma, K Zhu, L Yin, J Yang, J Zhang, H Wu, K Liu… - …, 2022 - Taylor & Francis
Stroke is a main cause of disability and death among adults in China, and acute ischemic
stroke accounts for 80% of cases. The key to ischemic stroke treatment is to recanalize the …