Publisher Summary This chapter discusses the anatomy and physiology of descending
control of nociceptive responses of dorsal horn neurons. Sensory pathways in vertebrates …

The third edition of this monograph continues to have the goal of providing an overview of
current thought about the spinal cord mechanisms that are responsible for sensory …

The organization in the brainstem of descending pathways of spinal inhibition was
examined in the lightly pentobarbital-anesthetized rat. Thresholds for focal electrical …

The efferent connections of the zona incerta (ZI) were studied experimentally in the rat by the
aid of the autoradiographic tracer technique. Small microelectrophoretic injections of tritiated …

Descending influences on the spinal nociceptive tail-flick (TF) reflex produced by focal
electrical stimulation and glutamate microinjection in the nuclei reticularis gigantocellularis …

Inhibition of the spinal nociceptive tail flick (TF) reflex by electrical stimulation throughout the
midbrain and medulla was examined and characterized in pentobarbital-anesthetized rats …

The organization in the brain stem of descending inhibitory control of spinal nociceptive
information was studied in anesthetized, paralyzed cats by quantitatively evaluating the …

Single and double retrograde tracer techniques were employed in cats to investigate:(1) the
topographical relationships between supraspinal neurons projecting to either the brachial or …

Afferent transmission in the spinal cord is subject to regulation by supra-spinally located
neurons. This concept originated with Sherrington and Sow-ton's (1915) observation that …

The relative contributions of nuclei within the rostral ventromedial medulla (RVM) involved in
mediating morphine induced antinociception from the periaqueductal gray (PAG) were …