Overcoming cancer chemotherapy resistance by the induction of ferroptosis

Y Wang, X Wu, Z Ren, Y Li, W Zou, J Chen… - Drug Resistance …, 2023 - Elsevier
Abstract Development of resistance to chemotherapy in cancer continues to be a major
challenge in cancer management. Ferroptosis, a unique type of cell death, is mechanistically …

Non-coding RNA in cancer drug resistance: Underlying mechanisms and clinical applications

X Zhou, X Ao, Z Jia, Y Li, S Kuang, C Du… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the most frequently diagnosed malignant diseases worldwide, posing a
serious, long-term threat to patients' health and life. Systemic chemotherapy remains the first …

Non-coding RNAs in lung cancer: molecular mechanisms and clinical applications

Y Liu, W Ding, J Wang, X Ao, J Xue - Frontiers in oncology, 2023 - frontiersin.org
Lung cancer (LC) is a heterogeneous disease with high malignant degree, rapid growth,
and early metastasis. The clinical outcomes of LC patients are generally poor due to the …

FOXO3a in cancer drug resistance

Y Liu, Y Wang, X Li, Y Jia, J Wang, X Ao - Cancer Letters, 2022 - Elsevier
Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

[HTML][HTML] The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation

DD Jia, H Jiang, YF Zhang, Y Zhang… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Piwi-interacting RNAs (piRNAs) are a class of short chain noncoding RNAs that are
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …

The FOXO family of transcription factors: key molecular players in gastric cancer

Y Liu, X Ao, Y Jia, X Li, Y Wang, J Wang - Journal of Molecular Medicine, 2022 - Springer
Gastric cancer (GC) is the fifth most frequently diagnosed cancer worldwide and the third
leading cause of cancer-related death with an oncological origin. Despite its decline in …

The critical roles of m6A RNA methylation in lung cancer: from mechanism to prognosis and therapy

MN Diao, XJ Zhang, YF Zhang - British Journal of Cancer, 2023 - nature.com
Lung cancer, a highly malignant disease, greatly affects patients' quality of life. N6-
methyladenosine (m6A) is one of the most common posttranscriptional modifications of …

A comprehensive insight into the correlation between ncRNAs and the Wnt/β-catenin signalling pathway in gastric cancer pathogenesis

R Akhavanfar, SG Shafagh, B Mohammadpour… - Cell Communication and …, 2023 - Springer
During the past decades, gastric cancer (GC) has emerged as one of the most frequent
malignancies with a growing rate of prevalence around the world. Despite considerable …

Underlying mechanisms of epithelial splicing regulatory proteins in cancer progression

Y Liu, Y Li, C Du, S Kuang, X Zhou, J Zhang… - Journal of Molecular …, 2022 - Springer
Cancer is the second-leading disease-related cause of global mortality after cardiovascular
disease. Despite significant advances in cancer therapeutic strategies, cancer remains one …

lncRNA-microRNA axis in cancer drug resistance: particular focus on signaling pathways

RO Saleh, MTS Al-Ouqaili, E Ali, S Alhajlah… - Medical Oncology, 2024 - Springer
Cancer drug resistance remains a formidable challenge in modern oncology, necessitating
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …