An update on immunotoxicity and mechanisms of action of six environmental mycotoxins

Y Sun, K Huang, M Long, S Yang, Y Zhang - Food and Chemical …, 2022 - Elsevier
Abstract Paradoxically, aflatoxin B1 (AFB1), ochratoxin A (OTA), deoxynivalenol (DON), T-2
toxin (T-2), fumonisin B1 (FB1), and zearalenone (ZEA) have both immunosuppressive and …

[HTML][HTML] Pathological consequences, metabolism and toxic effects of trichothecene T-2 toxin in poultry

J Vörösházi, Z Neogrády, G Mátis, M Mackei - Poultry Science, 2024 - Elsevier
Contamination of feed with mycotoxins has become a severe issue worldwide. Among the
most prevalent trichothecene mycotoxins, T-2 toxin is of particular importance for livestock …

[HTML][HTML] JNK molecule is a toxic target for IPEC-J2 cell barrier damage induced by T-2 toxin

F Chen, Y Wang, Y Chen, J Fan, C Zhang, X He… - Ecotoxicology and …, 2023 - Elsevier
The most prevalent contaminated mycotoxin in feed and grain is T-2 toxin. The T-2 toxin's
primary action target is the gut because it is the main organ of absorption. T-2 toxin can …

Mitochondrial damage induced by T-2 mycotoxin on human skin—fibroblast Hs68 cell line

E Janik-Karpinska, M Ceremuga, M Niemcewicz… - Molecules, 2023 - mdpi.com
T-2 toxin is produced by different Fusarium species and belongs to the group of type A
trichothecene mycotoxins. T-2 toxin contaminates various grains, such as wheat, barley …

Recent trends in fluorescent aptasensors for mycotoxin detection in food: Principles, constituted elements, types, and applications

X Yan, H Chen, G Du, Q Guo, Y Yuan, T Yue - Food Frontiers, 2022 - Wiley Online Library
Mycotoxins are the secondary metabolites of fungi in food and can be toxic to people.
Therefore, developing simple, sensitive, and specific detection methods to detect mycotoxins …

A fluorescence aptasensor based on controlled zirconium–based MOFs for the highly sensitive detection of T–2 toxin

X Zhao, Y Wang, J Li, B Huo, Y Qin, J Zhang… - … Acta Part A: Molecular …, 2021 - Elsevier
T–2 toxin is one of class A trichothecene mycotoxins produced by Fusarium, presenting
genotoxic, cytotoxicity, and immunotoxicity for animals and humans. Therefore, It is urgent to …

Updated Review of the Toxicity of Selected Fusarium Toxins and Their Modified Forms

A Pierzgalski, M Bryła, J Kanabus, M Modrzewska… - Toxins, 2021 - mdpi.com
Mycotoxins are one of the most dangerous food and feed contaminants, hence they have
significant influence on human and animal health. This study reviews the information …

Two birds with one stone: Gold “bridging” both nanozyme and immunosensor for sensitive double-response detection of T-2 toxin

R Shu, S Liu, C Zhao, X Lan, Y Li, J Wang, N Qiu… - Chemical Engineering …, 2024 - Elsevier
Developing immunosensors with nanozymes as signal labels has made a great deal of
progress and is no longer a novel concept. But even then, several research obstacles, eg …

Recent advances in assessing the effects of mycotoxins using animal models

AF Furian, MR Fighera, LFF Royes… - Current Opinion in Food …, 2022 - Elsevier
Food products are susceptible to mycotoxin contamination. The intoxication produces
distinct signs, depending on mycotoxin, duration, dose, and species susceptibility …

T-2 toxin induces ferroptosis by increasing lipid reactive oxygen species (ROS) and downregulating solute carrier family 7 member 11 (SLC7A11)

G Wang, S Qin, Y Zheng, C Xia, P Zhang… - Journal of Agricultural …, 2021 - ACS Publications
T-2 toxin is a trichothecene mycotoxin commonly found in animal feed and agricultural
products. Evidence indicates that T-2 toxin induces apoptosis and autophagy. This study …