Major depressive disorder (MDD) is one of the most prevalent psychiatric illnesses
worldwide which impairs the social functioning of the afflicted patients. Astrocytes promote …

Abstract N6-methyladenosine (m6A) modification, catalyzed by methyltransferase
complexes (MTCs), plays many roles in multifaceted biological activities. As the most …

Microglia-mediated inflammation is a major contributor to the brain damage in cerebral
ischemia and reperfusion (I/R) injury, and N6-Methyladenosine (m6A) has been implicated …

Recent evidence have indicated that ferroptosis, a novel iron-dependent form of non-
apoptotic cell death, plays a critical role in human cancers. Besides, emerging literatures …

RNA modifications known as epitranscriptomics have emerged as a novel layer of
transcriptomic regulation. Like the well-studied epigenetic modifications characterized in …

Amyotrophic lateral sclerosis (ALS) is a fatal disease. Skeletal muscles and motor neurons
(MNs) degenerate. ALS is a complex disease involving many genes in multiple tissues, the …

RNA methylation participates in the functional regulation of various biological processes,
affecting RNA translocation, alternative splicing, maturation, stability, and degradation to …

Abstract Objective The feature of Parkinson's disease (PD) is the heavy dopaminergic
neuron loss of substantia nigra pars compacta (SNpc), while glutaredoxin (GLRX) has been …

Abstract Benzo [a] pyrene (B [a] P) is a widespread environmental chemical pollutant that
has been linked to the development of various diseases. However, the specific mechanism …

The brain-gut axis (BGA) is a significant bidirectional communication pathway between the
brain and gut. Traumatic brain injury (TBI) induced neurotoxicity and neuroinflammation can …