Determination of novel highly effective necrostatin Nec-1s in rat plasma by high performance liquid chromatography hyphenated with quadrupole-time-of-flight mass …

P Mikuš, D Pecher, D Rauová, C Horváth, A Szobi… - Molecules, 2018 - mdpi.com
Necrostatins have been shown to retard necroptosis, a programmed necrotic-like cell death,
which has been shown to underlie pathophysiology of various diseases. Nec-1s, a novel …

[HTML][HTML] GSK2593074A blocks progression of existing abdominal aortic dilation

MK Khoury, T Zhou, H Yang, SR Prince, K Gupta… - JVS-vascular …, 2020 - Elsevier
Objective Receptor interacting proteins kinase 1 and 3 (RIPK1 and RIPK3) have been
shown to play essential roles in the pathogenesis of abdominal aortic aneurysms (AAAs) by …

Некроптоз и опыт его таргетной модуляции в контексте персонализированной медицины

ЮВ Дмитриев, ММ Галагудза - Российский журнал …, 2022 - persmed.elpub.ru
Аннотация В обзоре рассмотрены механизмы недавно описанного нового вида
программируемой клеточной гибели—некроптоза и его роль в развитии широкого …

Inhibition of MLKL impairs abdominal aortic aneurysm development by attenuating smooth muscle cell necroptosis

HN Nemade, D Mehrkens, HS Lottermoser, ZE Yilmaz… - bioRxiv, 2022 - biorxiv.org
Background Receptor-interacting serine/threonine-protein kinase 1 and 3 (RIPK1 and
RIPK3) dependent cell death has been identified as a crucial mediator of abdominal aortic …

[引用][C] 程序性细胞坏死在疾病中的研究进展

杨娜, 龙艺, 孙丽明 - 收藏, 2019

Die Bedeutung MLKL-und RIPK1 vermittelter nekroptotischer Prozesse in der Pathophysiologie der abdominalen Aortenaneurysmen

G Schwab - 2022 - kups.ub.uni-koeln.de
Die Nekroptose ist eine Form des regulierten Zelltodes, der durch Rezeptor-interagierende
Kinasen RIPK1 und RIPK3 induziert und im Gegensatz zur Apoptose durch das Substrat …

[HTML][HTML] Pathophysiology of aortic aneurysms: insights from animal studies

MK Khoury, AR Stranz, B Liu - Cardiology and cardiovascular …, 2020 - ncbi.nlm.nih.gov
Aortic aneurysms are defined as dilations of the aorta greater than 50 percent. Currently, the
only effective treatment for aortic aneurysms is surgical repair, which is recommended only …

Некроптоз: новая форма программируемой гибели клеток (обзор литературы)

ИС Греков, РБ Кондратюк - Медико-социальные проблемы семьи, 2020 - elibrary.ru
Современные достижения фундаментальной медицины позволили значительно
расширить наше представление о некоторых механизмахэлиминации клеточных …

The role of necroptosis in bladder cancer

BE Haupt - 2020 - repozitorij.svkst.unist.hr
Objectives: Although great progress has been achieved in terms of bladder cancer
management, survival rates for muscle invasive bladder cancer are still dismal, which …

[引用][C] Aus dem Herzzentrum der Universität zu Köln Klinik und Poliklinik für Innere Medizin III Direktor: Universitätsprofessor Dr. med. St. Baldus

GF Schwab