Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review
R Margiana, A Markov, AO Zekiy, MU Hamza… - Stem Cell Research & …, 2022 - Springer
The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide
consideration because of their immense potential for immunomodulation and their …
consideration because of their immense potential for immunomodulation and their …
Treatment of renal fibrosis—turning challenges into opportunities
BM Klinkhammer, R Goldschmeding, J Floege… - Advances in chronic …, 2017 - Elsevier
Current treatment modalities are not effective in halting the progression of most CKD. Renal
fibrosis is a pathological process common to all CKD and thereby represents an excellent …
fibrosis is a pathological process common to all CKD and thereby represents an excellent …
Combination of adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia–reperfusion injury
Background In this study, we tested the hypothesis that a combined adipose-derived
mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy protected rat …
mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy protected rat …
The role of miRNA in renal fibrosis leading to chronic kidney disease
A Gluba-Sagr, B Franczyk, M Rysz-Górzyńska… - Biomedicines, 2023 - mdpi.com
Chronic kidney disease (CKD) is an important health concern that is expected to be the fifth
most widespread cause of death worldwide by 2040. The presence of chronic inflammation …
most widespread cause of death worldwide by 2040. The presence of chronic inflammation …
Pathophysiology and genetics of salt-sensitive hypertension
Most hypertensive cases are primary and heavily associated with modifiable risk factors like
salt intake. Evidence suggests that even small reductions in salt consumption reduce blood …
salt intake. Evidence suggests that even small reductions in salt consumption reduce blood …
Mesenchymal stromal cell therapy in ischemia/reperfusion injury
Ischemia/reperfusion injury (IRI) represents a worldwide public health issue of increasing
incidence. IRI may virtually affect all organs and tissues and is associated with significant …
incidence. IRI may virtually affect all organs and tissues and is associated with significant …
[HTML][HTML] Adipose-derived mesenchymal stem cell-derived exosomes alleviate overwhelming systemic inflammatory reaction and organ damage and improve outcome …
CL Chang, PH Sung, KH Chen, PL Shao… - American journal of …, 2018 - ncbi.nlm.nih.gov
This study tested the hypothesis that healthy adipose-derived mesenchymal stem cell
(ADMSC)-derived exosomes (HMSC EXO) and apoptotic (A)(induced by 12 h hypoxia/12 h …
(ADMSC)-derived exosomes (HMSC EXO) and apoptotic (A)(induced by 12 h hypoxia/12 h …
Renoprotective approaches and strategies in acute kidney injury
Y Yang, M Song, Y Liu, H Liu, L Sun, Y Peng… - Pharmacology & …, 2016 - Elsevier
Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and
increasing prevalence. Decades of research have suggested numerous chemical and …
increasing prevalence. Decades of research have suggested numerous chemical and …
Exosomes derived from ADSCs attenuate sepsis-induced lung injury by delivery of circ-fryl and regulation of the miR-490-3p/SIRT3 pathway
W Shen, X Zhao, S Li - Inflammation, 2022 - Springer
Sepsis-induced lung injury is a clinical syndrome characterized by injury of alveolar
epithelium cells (AECs). Previous investigations illustrate that exosomes secreted from …
epithelium cells (AECs). Previous investigations illustrate that exosomes secreted from …
Mesenchymal stem cell-derived extracellular vesicles for renal repair
A Aghajani Nargesi, LO Lerman… - Current gene therapy, 2017 - ingentaconnect.com
Introduction: Transplantation of autologous mesenchymal stem cells (MSCs) has been
shown to attenuate renal injury and dysfunction in several animal models, and its efficacy is …
shown to attenuate renal injury and dysfunction in several animal models, and its efficacy is …