Split T Cell Tolerance against a Self/Tumor Antigen: Spontaneous CD4+ but Not CD8+ T Cell Responses against p53 in Cancer Patients and Healthy Donors

T Tsuji, J Matsuzaki, E Ritter, A Miliotto, G Ritter… - PLoS …, 2011 - journals.plos.org
Analyses of NY-ESO-1-specific spontaneous immune responses in cancer patients revealed
that antibody and both CD4+ and CD8+ T cell responses were induced together in cancer …

Immunotherapy for the treatment of breast cancer

MA Moreno Ayala, MF Gottardo, AS Asad… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Breast cancer is the most common cancer as well as the first cause of death by
cancer in women worldwide. Although routine treatment improves the outcome of early …

[PDF][PDF] Dendritic cells as therapeutic agents against cancer

EA Eksioglu, S Eisen, V Reddy - Front Biosci, 2010 - article.imrpress.com
Introduction 3. DC Immunobiology 4. Dendritic Cell Subpopulations 5. The type1/type 2
dualism and cancer 6. Generation of DC for Therapy 7. Consideration of DC Maturation …

A novel HLA-A2–restricted CTL epitope of tumor-associated antigen L6 can inhibit tumor growth in vivo

SH Tu, HI Huang, SI Lin, HY Liu, YP Sher… - Journal of …, 2012 - journals.lww.com
Vaccines utilizing cytotoxic T lymphocyte (CTL) epitopes are promising for the treatment of
cancer and chronic infectious diseases. Tumor-associated antigen L6 (TAL6) is …

In Vivo Imaging of Lymph Node Migration of MNP- and 111In-Labeled Dendritic Cells in a Transgenic Mouse Model of Breast Cancer (MMTV-Ras)

C Martelli, M Borelli, L Ottobrini, V Rainone… - Molecular imaging and …, 2012 - Springer
Purpose The authors present a protocol for the in vivo evaluation, using different imaging
techniques, of lymph node (LN) homing of tumor-specific dendritic cells (DCs) in a murine …

Studies on mRNA electroporation of immature and mature dendritic cells: effects on their immunogenic potential

Ö Met, J Eriksen, IM Svane - Molecular biotechnology, 2008 - Springer
Previous studies have shown that mRNA-electroporated dendritic cells (DCs) are able to
process and present tumor-associated antigens, leading to the activation of tumor-specific T …

Single-step antigen loading and maturation of dendritic cells through mRNA electroporation of a tumor-associated antigen and a TriMix of costimulatory molecules

D Benteyn, AMT Van Nuffel, S Wilgenhof… - … Vaccines: Methods and …, 2014 - Springer
Dendritic cells (DC) are key players in several types of cancer vaccines. Large numbers of
DC can easily be generated in closed systems from the monocyte fraction of the peripheral …

Dendritic cell vaccination

O Proudfoot, D Pouniotis, KC Sheng… - Expert review of …, 2007 - Taylor & Francis
There has been a surge of interest in the use of dendritic cell (DC) vaccination as cellular
immunotherapy for numerous cancers. Despite some encouraging results, this therapeutic …

Клеточная иммунотерапия-современный подход к лечению онкологических заболеваний

ЮН Лежнин, АЮ Христиченко… - Медицинская …, 2018 - cyberleninka.ru
Выяснение механизмов врожденного иммунитета, отвечающих за защиту от
возникновения злокачественных опухолей, способствует разработке новых подходов к …

Closing the manufacturing process of dendritic cell vaccines transduced with adenovirus vectors

D Gulen, F Abe, S Maas, E Reed, K Cowan… - International …, 2008 - Elsevier
Anticancer immunotherapy using dendritic cell (DC) based vaccines provides an adjuvant
therapeutic strategy that is not cross reactive with conventional therapeutics. However …