Does the immunocompetent status of cancer patients have an impact on therapeutic DC vaccination strategies?

S Martin Lluesma, M Graciotti, CLL Chiang… - Vaccines, 2018 - mdpi.com
Although different types of therapeutic vaccines against established cancerous lesions in
various indications have been developed since the 1990s, their clinical benefit is still very …

Interaction of current cancer treatments and the immune system: implications for breast cancer therapeutics

PH Tan, AS Lota - Expert Opinion on Pharmacotherapy, 2008 - Taylor & Francis
Early diagnosis and treatment of breast cancer may account for the current improvement in
the mortality of breast cancer. However, achieving a complete 'cure'is the holy grail of cancer …

Induction of cytotoxic T cell response against HCA661 positive cancer cells through activation with novel HLA-A∗ 0201 restricted epitopes

PHS Pang, KT Chan, LYW Tse, RCF Chan, YK Cheung… - Cancer letters, 2007 - Elsevier
HCA661 is a cancer–testis (CT) antigen frequently expressed in human hepatocellular
carcinoma (HCC). To search for immunogenic peptides of HCA661, bioinformatics analysis …

Identification of a cyclin B1-derived CTL epitope eliciting spontaneous responses in both cancer patients and healthy donors

RS Andersen, RB Sørensen, C Ritter, IM Svane… - Cancer immunology …, 2011 - Springer
With the aim to identify cyclin B1-derived peptides with high affinity for HLA-A2, we used
three in silico prediction algorithms to screen the protein sequence for possible HLA-A2 …

Cell culture plastics with immobilized interleukin‐4 for monocyte differentiation

M Hansen, GM Hjortø, Ö Met… - … Research Part A, 2011 - Wiley Online Library
Standard cell culture plastic was surface modified by passive adsorption or covalent
attachment of interleukin (IL)‐4 and investigated for its ability to induce differentiation of …

T1-2 期乳腺癌患者腋窝淋巴结生发中心和窦组织细胞增生与淋巴结转移的关系

苏震东, 苏光启, 李小强 - 上海交通大学学报(医学版), 2010 - xuebao.shsmu.edu.cn
目的探讨T1-2 期乳腺癌患者腋窝淋巴结生发中心增生(GH) 和窦组织细胞增生(SH)
与淋巴结转移的关系. 方法选取104 例T1-2 期乳腺导管癌患者, HE 染色法检测腋窝淋巴结GH …

Studies on the Role of Necroptosis Proteins RIPK3 and MLKL in Resistance to Viral Infection and on the Role of CD8 T-Cells Induced by mRNA-LNP Vaccines in …

B Montoya - 2023 - search.proquest.com
Receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain-like
pseudokinase (MLKL) are proteins critical for necroptosis, a mechanism of programmed cell …

Resuscitating the Guardian: Current Progress in p53-Based Anti-Tumor Therapy

L Alfason, W Li, F Altaf, S Wu, V Kasim - Onco Therapeutics, 2021 - dl.begellhouse.com
The discovery of TP53, the gene that encodes tumor suppressor p53, over 40 years ago is a
breakthrough for deciphering the molecular mechanism of the most fundamental biological …

[PDF][PDF] Иммунофенотип и функциональные свойства моноцитарных дендритных клеток больных раком молочной железы

ЛП Титов, АЕ Гончаров, ЛА Путырский… - Здравоохранение …, 2010 - researchgate.net
Ìàòåðèàë è ìåòîäû. Èññëåäîâàíèå ïðåäñòàâëÿåò ñîáîé ñåðèþ ýêñïåðèìåíòîâ in vitro. Áûëè
âçÿòû îáðàçöû ïåðèôåðè÷ åñêîé êðîâè äîíîðîâ è áîëüíûõ ðàêîì ìîëî÷ íîé æåëåçû II ñòàäèè …

Peptide specific expansion of CD8+ T cells by recombinant plate bound MHC/peptide complexes

EGW Schmidt, S Buus, M Thorn, A Stryhn… - Journal of …, 2009 - Elsevier
Development of methods for efficient in vitro stimulation and expansion of peptide specific
CD8+ T cells is compelling not only with respect to adoptive T cell therapy but also regarding …