Ferroptosis is an iron-driven cell death modality characterized by iron accumulation and
excessive lipid peroxidation. Ferroptosis is closely related to mitochondrial function, as …

Diabetic kidney disease is one of the complications of diabetes mellitus, which can
eventually progress to end-stage kidney disease. The increasing prevalence of diabetic …

Background Ferroptosis is a type of cell death caused by excessive iron-induced
peroxidation. It has been found to be involved in a variety of diseases, and natural products …

Chlorantraniliprole (CAP) is a bis-amide pesticide used for pest control mainly in agricultural
production activities and rice-fish co-culture systems. CAP residues cause liver damage in …

Doxorubicin is a widely used anticancer drug in clinical practice for the treatment of various
human tumors. However, its administration is associated with cardiotoxicity. Administration …

Background The prevalence of ferroptosis in diabetic kidney tubules has been documented,
yet the underlying mechanism remains elusive. The aim of this study was to ascertain the …

Abstract Background Astragaloside IV (As-IV) and Tanshinone IIA (Ta-IIA) are the main
ingredients of traditional Chinese medicinal Astragalus membranaceus (Fisch.) Bunge and …

Ethnopharmacological relevance Iron is an essential micronutrient for maintaining
physiological activities, especially for highly active cardiomyocytes. Inappropriate iron …

Ferroptosis, distinct from apoptosis, necrosis, autophagy, and other types of cell death, is a
novel iron-dependent regulated cell death characterized by the accumulation of lipid …

Background Transient receptor potential (TRP) ankyrin 1 (TRPA1) could mediate ozone-
induced lung injury. Optic Atrophy 1 (OPA1) is one of the significant mitochondrial fusion …