The mouse as a model to investigate sex steroid metabolism in the normal and pathological prostate
KM McNamara, DJ Handelsman… - The Journal of steroid …, 2012 - Elsevier
Metabolism of sex steroids within the prostate is an important factor affecting its growth and
pathology. Mouse models with genetic gain-and especially loss-of-function have …
pathology. Mouse models with genetic gain-and especially loss-of-function have …
5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores
AB Opoku-Acheampong, JN Henningson, AP Beck… - PLoS …, 2017 - journals.plos.org
Background The contribution of 5α-reductase 1 and 5α-reductase 2 to prostate cancer
development and progression is not clearly understood. TRAMP mice are a common …
development and progression is not clearly understood. TRAMP mice are a common …