Progesterone and its metabolites promote the viability of neurons in the brain and spinal
cord. Their neuroprotective effects have been documented in different lesion models …

Pregnancy is a complex process requiring tremendous physiological changes in the mother
in order to fulfill the needs of the growing fetus, and to give birth, expel the placenta and …

There is emerging evidence that early uterine development in humans is an important
determinant of conditions such as ontogenetic progesterone resistance, menstrual …

The utility and safety of postmenopausal hormone replacement therapy has recently been
put into question by large clinical trials. Their outcome has been extensively commented …

We studied the effects of estradiol (E2) and progesterone (P) on progesterone receptor (PR)
isoforms gene expression in the brain of ovariectomised female and gonadectomised male …

Progesterone has been suggested to be involved in the functions of the nervous system, but
it has yet to be examined in humans. Progesterone has also been postulated to be involved …

Expression of estrogen (ER) and progesterone (PR) receptors was investigated in cultured
human normal myometrial cells (non‐pregnant uterus, fertile period). The ER and PR …

Expression of the receptor tyrosine kinase KIT on cells referred to as interstitial cells of Cajal
(ICC) has been instrumental during the past decade in the tremendous interest in cells in the …

Each synthetic progestins has its own specific activities on different tissues, which can vary
significantly between progestins of different classes and even within the same class. Indeed …

Progesterone has neuroprotective effects in the injured and diseased spinal cord and after
traumatic brain injury (TBI). In addition to intracellular progesterone receptors (PR) …