Human autoantibodies (auto‐Abs) neutralizing type I IFNs were first discovered in a woman
with disseminated shingles and were described by Ion Gresser from 1981 to 1984. They …

Type I and type III interferons (IFNs) constitute a key antiviral defense systems of the body,
inducing viral resistance to cells and mediating diverse innate and adaptive immune …

We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19
pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-α2 in 10 patients …

The essential and redundant functions of human type I and II interferons (IFNs) have been
delineated over the last three decades by studies of patients with inborn errors of immunity …

Objective We sought to explore the prevalence of type I interferon-neutralizing antibodies in
a Chinese cohort and its clinical implications during the Omicron variant wave of SARS-CoV …

It has now been 20 years since the original discovery of the interferon λ (IFN-λ) family
(Kotenko et al.,; Sheppard et al.,) and 10 years since the subsequent discovery of IFN-λ4 …

Interferons (IFNs) are a critical component of innate immune defenses and limit viral disease
severity. To advance studies on IFNs and their neutralization by pathogenic autoantibodies …