A vital trial in gene delivery implicates the want for competent and safe delivery systems to
announce therapeutic genes into target cells. Virus vectors are disparaged for genetic …

A deeper knowledge on the formation and biological fate of polymer based gene vectors is
needed for their translation into therapy. Here, polyplexes of polyethyleneimine (PEI) and …

Biomacromolecule drugs of nucleic acids and proteins/peptides have occupied growing
share of global pharmaceutical market, but their biomedical application faces substantial …

Quantum dots (QDs) are renowned for their remarkable optoelectronic properties, making
them suitable for applications such as bioimaging and optoelectronics. However, their use in …

Introduction Owing to the unique properties of graphene, including large specific surface
area, excellent thermal conductivity, and optical absorption, graphene-family nanomaterials …

Articular cartilage defects caused by various reasons are relatively common in clinical
practice, but the lack of efficient therapeutic methods remains a substantial challenge due to …

Background: Gene delivery is a promising technology for treating diseases linked to
abnormal gene expression. Since nucleic acids are the therapeutic entities in such …

With the discovery of genetic factors of diseases, gene therapy has become a promising
treatment option for many diseases, especially for different types of cancer, one of which is …

Star polymers of N, N′-dimethylaminoethyl methacrylate (DMAEMA) and hydroxyl-bearing
oligo (ethylene glycol) methacrylate (OEGMA-OH) were used as pDNA and mRNA carriers …

Modified polyethyleneimine (PEI) has been widely used as siRNA delivery agents. Here, a
new Triton X-100-modified low-molecular-weight PEI siRNA delivery agent is developed …