Exosome processing and characterization approaches for research and technology development
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
[HTML][HTML] Mesenchymal stem/stromal cells in cancer therapy
T Lan, M Luo, X Wei - Journal of Hematology & Oncology, 2021 - Springer
The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …
marrow in 1976, have been identified in nearly all tissues of human body now. The …
Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy
Neutrophils are the most abundant innate immune cells in human circulation; however, their
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …
[HTML][HTML] Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery
S Waheed, Z Li, F Zhang, A Chiarini, U Armato… - Journal of …, 2022 - Springer
The rapid advancement of nanomedicine and nanoparticle (NP) materials presents novel
solutions potentially capable of revolutionizing health care by improving efficacy …
solutions potentially capable of revolutionizing health care by improving efficacy …
[HTML][HTML] Revolutionizing anti-tumor therapy: unleashing the potential of B cell-derived exosomes
B cells occupy a vital role in the functioning of the immune system, working in tandem with T
cells to either suppress or promote tumor growth within the tumor microenvironment (TME) …
cells to either suppress or promote tumor growth within the tumor microenvironment (TME) …
Integrated SERS-vertical flow biosensor enabling multiplexed quantitative profiling of serological exosomal proteins in patients for accurate breast cancer subtyping
Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …
[HTML][HTML] Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment
S Tan, Y Yang, W Yang, Y Han, L Huang… - Journal of Experimental …, 2023 - Springer
Metabolic reprogramming is one of the hallmarks of cancer. As nutrients are scarce in the
tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet …
tumor microenvironment (TME), tumor cells adopt multiple metabolic adaptations to meet …
Biomembrane-based nanostructures for cancer targeting and therapy: from synthetic liposomes to natural biomembranes and membrane-vesicles
The translational success of liposomes in chemotherapeutics has already demonstrated the
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …
great potential of biomembrane-based nanostructure in effective drug delivery. Meanwhile …
[HTML][HTML] Exosomes as smart drug delivery vehicles for cancer immunotherapy
H Zhang, S Wang, M Sun, Y Cui, J Xing… - Frontiers in …, 2023 - frontiersin.org
Exosomes (Exos) as drug delivery vehicles have been widely used for cancer
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …
[HTML][HTML] The potential role of exosomal circRNAs in the tumor microenvironment: insights into cancer diagnosis and therapy
Exosomes are multifunctional regulators of intercellular communication by carrying various
messages under both physiological and pathological status of cancer patients …
messages under both physiological and pathological status of cancer patients …