While checkpoint blockade immunotherapy as a promising clinical modality has
revolutionized cancer treatment, it is of benefit to only a subset of patients because of the …

Delivering therapeutics to the central nervous system (CNS) is difficult because of the blood–
brain barrier (BBB). Therapeutic delivery across the tight junctions of the BBB can be …

Extracellular vesicles (EVs) contain various bioactive molecules such as DNA, RNA, and
proteins, and play a key role in the regulation of cancer progression. Furthermore, cancer …

Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …

Exosomes are natural extracellular nanovesicles (30–150 nm in diameter) with the ability to
interact with and be taken up by specific cells. They are being explored as delivery systems …

Exosomes are cell-derived vesicles with a lipid bilayer membrane that play important roles
in intercellular communication. They provide an unprecedented opportunity for the …

Recent studies have found that exosomes or extracellular vehicles (EVs) are associated with
cancer metastasis, disease progression, diagnosis, and treatment, leading to a rapidly …

Liquid biopsy is a diagnostic repeatable test, which in last years has emerged as a powerful
tool for profiling cancer genomes in real-time with minimal invasiveness and tailoring …

Cancer, one of the leading causes of death, has seriously threatened public health.
However, there is still a lack of effective treatments. Nowadays, photodynamic therapy …

Lymph node (LN) metastasis occurs frequently in pancreatic ductal adenocarcinoma
(PDAC) and predicts poor prognosis for patients. The KRASG12D mutation confers an …