Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

HE Bøtker, D Hausenloy, I Andreadou… - Basic research in …, 2018 - Springer
The potential for ischemic preconditioning to reduce infarct size was first recognized more
than 30 years ago [180]. Despite extension of the concept to ischemic postcondition‑ing …

The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities

K McCafferty, S Forbes… - Disease models & …, 2014 - journals.biologists.com
Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of
blood supply to the affected area causes significant tissue damage. This is known as …

No sex-related differences in infarct size, no-reflow, and protection by ischaemic pre-conditioning in Göttingen minipigs

P Kleinbongard, H Lieder, A Skyschally… - Cardiovascular …, 2023 - academic.oup.com
Aims Female sex has been proposed to be cardioprotective per se. Studies with myocardial
ischaemia/reperfusion and infarct size as endpoint have demonstrated cardioprotection in …

The effect of geniste on Aβ25–35-induced PC12 cell apoptosis through the JNK-dependent Fas pathway

Y Zheng, F You, Q Li, J Chen, H Yang - Food & function, 2016 - pubs.rsc.org
The β-amyloid protein (Aβ) is considered to be the key factor for inducing Alzheimer's
disease (AD). In recent years, the neuroprotective effects of genistein have drawn increasing …

Ischaemic conditioning strategies for the nephrologist: a promise lost in translation?

K McCafferty, C Byrne… - Nephrology Dialysis …, 2014 - academic.oup.com
Over the last quarter of a century, a huge effort has been made to develop interventions that
can minimise ischaemia reperfusion injury. The most potent of these are the ischaemic …

Postconditioning is protective in renal reperfusion injury only in male rats. A gender difference study

A Mahmoudi, M Kadkhodaee, F Golab… - Acta Physiologica …, 2015 - akjournals.com
Purpose: We investigated the impact of sex on the protective effect of postconditioning
(POC), a series of brief ischemia-reperfusion (IR) cycles at the reperfusion onset, as a …

[PDF][PDF] Involvement of Estrogen Receptor and Mitochondrial K

A Kumar, O Goshain, B Sharma… - … J Pharm Sci, 2022 - pdfs.semanticscholar.org
The present study was designed to investigate the role of estrogen receptor and
KATPchannel in cardioprotective effect of remote aortic preconditioning in rat heart. Remote …

[图书][B] Menstrual Cycle and the Vascular Properties of Remote Preconditioning

S Rachel - 2019 - search.proquest.com
PURPOSE: A promising therapeutic intervention to counteract endothelial
ischemia/reperfusion (I/R) injury is ischemic preconditioning (IPC). Limited data from …

[HTML][HTML] Geschlechtsspezifische Effekte von humanem Plasma nach Ischämischer Fernpräkonditionierung des älteren Menschen auf Infarktgröße und Hämodynamik …

AA Aytulun - 2018 - docserv.uni-duesseldorf.de
Methodik: Für diese Studie lagen Genehmigungen der Ethikkommission (Studie 3911) und
des Tierschutzbeauftragten (Nr. O 27/12) der Heinrich-Heine Universität Düsseldorf vor. An …

Myocardial ischaemia–reperfusion injury and its reduction by remote ischaemic preconditioning in health and diabetes mellitus

SA Edroos - 2014 - figshare.le.ac.uk
Myocardial infarction is the main cause of death in the United Kingdom. Early reperfusion of
coronary artery occlusion has greatly improved mortality, though restoration of blood supply …