Obesity and breast cancer: role of leptin

F Sánchez-Jiménez, A Pérez-Pérez… - Frontiers in …, 2019 - frontiersin.org
Obesity-related breast cancer is an important threat that affects especially post-menopausal
women. The link between obesity and breast cancer seems to be relying on the …

Molecular mechanisms of western diet-induced obesity and obesity-related carcinogenesis—A narrative review

D Lathigara, D Kaushal, RB Wilson - Metabolites, 2023 - mdpi.com
The present study aims to provide a narrative review of the molecular mechanisms of
Western diet-induced obesity and obesity-related carcinogenesis. A literature search of the …

[HTML][HTML] Inflammation, immunosuppressive microenvironment and breast cancer: opportunities for cancer prevention and therapy

SK Deshmukh, SK Srivastava, T Poosarla… - Annals of …, 2019 - ncbi.nlm.nih.gov
Breast cancer is the most commonly diagnosed malignancy and a leading cause of cancer-
related death in women worldwide. It also exhibits pronounced racial disparities in terms of …

The effects of resistance exercise on biomarkers of breast cancer prognosis: a pooled analysis of three randomized trials

KM Winters-Stone, LJ Wood, S Stoyles… - … , biomarkers & prevention, 2018 - AACR
Background: Using a secondary data analysis from randomized controlled trials comparing
one year of resistance exercise (n= 109) to a placebo control condition (n= 106) in …

Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells

S Afrin, M El Sabah, A Manzoor… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Objective Obesity and its consequences are among the biggest challenges facing the
healthcare system. Uterine leiomyomas are the most common gynecologic tumors. The risk …

Links between inflammation and postoperative cancer recurrence

T Kinoshita, T Goto - Journal of clinical medicine, 2021 - mdpi.com
Despite complete resection, cancer recurrence frequently occurs in clinical practice. This
indicates that cancer cells had already metastasized from their organ of origin at the time of …

Effects of exercise on immune cells with tumor-specific activity in breast cancer patients and survivors: a systematic review and meta-analysis

AM Lavín-Pérez, D Collado-Mateo, S Abbasi… - Supportive Care in …, 2023 - Springer
Exercise is effective for improving the physical and psychological health of breast cancer
patients. However, there is still controversy around its role on the immune system. Therefore …

Chemopreventive and anticancer property of selenoproteins in obese breast cancer

S Bevinakoppamath, AM Saleh Ahmed… - Frontiers in …, 2021 - frontiersin.org
Obesity is a significant risk factor for various cancers including breast cancer resulting in an
increased risk of recurrence as well as morbidity and mortality. Extensive studies on various …

[HTML][HTML] HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β

K Tawara, H Scott, J Emathinger, C Wolf, D LaJoie… - Oncotarget, 2019 - ncbi.nlm.nih.gov
Chronic inflammation has been recognized as a risk factor for the development and
maintenance of malignant disease. Cytokines such as interleukin-6 (IL-6), oncostatin M …

COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice

RM Gonçalves, M Delgobo, JP Agnes, RN das Neves… - Cancer Letters, 2021 - Elsevier
Obesity is a major risk factor for breast cancer, especially in post-menopausal women. In the
breast tissue of obese women, cyclooxygenase-2 (COX-2)-dependent prostaglandin E2 …