Pyroptosis is a programmed cell death characterized by swift plasma membrane disruption
and subsequent release of cellular contents and pro-inflammatory mediators (cytokines) …

Owing to the variety and complexity of ocular diseases and the natural ocular barriers, drug
therapy for ocular diseases has significant limitations, such as poor drug targeting to the site …

Contact lens-related complications are common, affecting around one third of wearers,
although most are mild and easily managed. Contact lenses have well-defined anatomical …

Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS; the most common
phenotype of corticobasal degeneration) are tauopathies with a relentless course, usually …

The present study was set out to address the therapeutic efficacy of human adipose tissue
stem cells derived extracellular vesicles (hADSC-Evs) in a mouse model of dry eye disease …

Dry eye disease (DED) is a multifactorial condition resulting from reduced tear secretion
from the lacrimal glands, increased tear water evaporation or the production of poor-quality …

Metabolomics refers to the high-through untargeted or targeted screening of metabolites in
biofluids, cells, and tissues. Metabolome reflects the functional states of cells and organs of …

Objective To evaluate and compare the symptomatology and clinical findings in
hyposecretory dry eye of the treatment with platelet‐rich plasma (PRP) and artificial tears of …

Sjogren's syndrome (SS) is characterized as an autoimmune disorder targeting secretory
glands, including the lacrimal and salivary glands, causing dry eye and dry mouth …

Multiple myeloma (MM) remains an incurable haematological malignancy typically
characterised by multiple relapses requiring ongoing sequential therapy. 1 This treatment …