Excessive trabeculation, often referred to as “noncompacted” myocardium, has been
described at all ages, from the fetus to the adult. Current evidence for myocardial …

Excessive trabeculation of the cardiac left ventricular wall is a complex phenotypic substrate
associated with various physiological and pathological processes. There has been …

Importance Genetic testing can guide management of both cardiomyopathies and
arrhythmias, but cost, yield, and uncertain results can be barriers to its use. It is unknown …

Inherited cardiovascular diseases are highly heterogeneous conditions with multiple genetic
loci involved. The application of advanced molecular tools, such as Next Generation …

Left ventricular noncompaction: a disorder with genotypic and phenotypic heterogeneity—a
narrative review - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Left ventricular noncompaction (LVNC) cardiomyopathy is a disorder that can be
complicated by heart failure, arrhythmias, thromboembolism, and sudden cardiac death. The …

Cardiomyopathies are myocardial diseases characterized by mechanical and electrical
dysfunction of the heart muscle which could lead to heart failure and life-threatening …

BACKGROUND: Less than 40% of patients with dilated cardiomyopathy (DCM) have a
pathogenic/likely pathogenic genetic variant identified. TBX20 has been linked to congenital …

In the realm of cardiovascular health, isolated left ventricular noncompaction (LVNC) stands
out for its distinct morphological features and the clinical challenges it presents, particularly …

Classic infantile Pompe disease is characterized by a severe phenotype with
cardiomyopathy and hypotonia. Cardiomyopathy is generally hypertrophic and rapidly …