Inferring causal phenotype networks using structural equation models

GJM Rosa, BD Valente, G de los Campos… - Genetics Selection …, 2011 - Springer
Phenotypic traits may exert causal effects between them. For example, on the one hand,
high yield in dairy cows may increase the liability to certain diseases and, on the other hand …

[HTML][HTML] Invited review: Recursive models in animal breeding: Interpretation, limitations, and extensions

L Varona, O González-Recio - Journal of Dairy Science, 2023 - Elsevier
Structural equation models allow causal effects between 2 or more variables to be
considered and can postulate unidirectional (recursive models; RM) or bidirectional …

Inference of gene regulatory networks with sparse structural equation models exploiting genetic perturbations

X Cai, JA Bazerque, GB Giannakis - PLoS computational biology, 2013 - journals.plos.org
Integrating genetic perturbations with gene expression data not only improves accuracy of
regulatory network topology inference, but also enables learning of causal regulatory …

[HTML][HTML] Application of single-step genomic evaluation using multiple-trait random regression test-day models in dairy cattle

HR Oliveira, DAL Lourenco, Y Masuda, I Misztal… - Journal of dairy …, 2019 - Elsevier
Test-day traits are important for genetic evaluation in dairy cattle and are better modeled by
multiple-trait random regression models (RRM). The reliability and bias of genomic …

[HTML][HTML] Prediction accuracies and genetic parameters for test-day traits from genomic and pedigree-based random regression models with or without heat stress …

M Bohlouli, S Alijani, S Naderi, T Yin, S König - Journal of dairy science, 2019 - Elsevier
The aim of this study was to compare genetic (co) variance components and prediction
accuracies of breeding values from genomic random regression models (gRRM) and …

[HTML][HTML] Longitudinal study on the effects of intramammary infection with non-aureus staphylococci on udder health and milk production in dairy heifers

D Valckenier, S Piepers, YH Schukken… - Journal of Dairy …, 2021 - Elsevier
We conducted a longitudinal study to evaluate the effect of non-aureus staphylococci (NAS)
causing subclinical intramammary infections (IMI) on quarter milk somatic cell count (qSCC) …

Is structural equation modeling advantageous for the genetic improvement of multiple traits?

BD Valente, GJM Rosa, D Gianola, XL Wu, K Weigel - Genetics, 2013 - academic.oup.com
Structural equation models (SEMs) are multivariate specifications capable of conveying
causal relationships among traits. Although these models offer insights into how phenotypic …

Test‐day somatic cell score, fat‐to‐protein ratio and milk yield as indicator traits for sub‐clinical mastitis in dairy cattle

J Jamrozik, LR Schaeffer - Journal of Animal Breeding and …, 2012 - Wiley Online Library
Test‐day (TD) records of milk, fat‐to‐protein ratio (F: P) and somatic cell score (SCS) of first‐
lactation Canadian Holstein cows were analysed by a three‐trait finite mixture random …

Selection index based on random regression model in 'Tahiti'acid lime

RG Malikouski, RS Alves, MA Peixoto, FM Ferreira… - Euphytica, 2022 - Springer
An accurate and efficient statistical method for repeated measures analysis and selection of
scion/rootstock combinations (SRC) is a fundamental prerequisite for genetic progress in …

Deciphering hybrid larch reaction norms using random regression

A Marchal, CD Schlichting, R Gobin… - G3: Genes …, 2019 - academic.oup.com
The link between phenotypic plasticity and heterosis is a broad fundamental question, with
stakes in breeding. We report a case-study evaluating temporal series of wood ring traits of …