Systemic sclerosis is a severe connective tissue disease in which inflammation and
autoimmunity are associated with progressive tissue remodeling and fibrosis of the skin and …

The conceptualization of precision medicine and the determinants of individuality in disease
predisposition and treatment response represent a methodological revival of an emblematic …

University of Groningen Re-direction of interferon gamma and its signaling moiety Bansal, Ruchi
Page 1 University of Groningen Re-direction of interferon gamma and its signaling moiety …

Pulmonary fibrosis (PF) is a progressive fatal disorder. Bleomycin (BLM) is a widely used
chemotherapeutic agent causing PF. Numerous agents have been investigated to prevent …

ABSTRACT Background/Aims: Hepatic stellate cells (HSCs), following transdifferentiation to
myofibroblasts plays a key role in hepatic fibrosis through the production of extracellular …

The Th purpose of this chapter is to provide a current view of the contributions of the distal
lung epithelium to the pathobiology of interstitial lung diseases (ILDs). Although there are a …

Εισαγωγή: Η ιδιοπαθής πνευμονική ίνωση (ΙΠΙ) χαρακτηρίζεται από προοδευτική επιδείνωση
της αναπνευστικής λειτουργίας, με τελική κατάληξη τον θάνατο. Μέχρι σήμερα, δεν έχει …

Idiopatická plicní fibróza (IPF), exogenní alergická alveolitida (EAA) a sarkoidóza jsou
intersticiální plicní procesy (IPP) s odlišnou patogenezí. Zatím co IPF představuje primární …

Prostate cancer is the second leading cause of cancer death in men. While prostate specific
antigen (PSA) is currently the best biomarker available, its use has many limitations. This …

Fibrogenesis in Crohns disease (CD) leads to intestinal stricture and fibrostenosing
phenotype. Despite the remarkable success in the last years in medical therapies for CD …