Toxicity of nanomaterials: exposure, pathways, assessment, and recent advances
Growth in production of manufactured goods and the use of nanomaterials in consumer
products has mounted in the past few decades. Nanotoxicology or toxicity assessment of …
products has mounted in the past few decades. Nanotoxicology or toxicity assessment of …
A review on viral biosensors to detect human pathogens
RL Caygill, GE Blair, PA Millner - Analytica chimica acta, 2010 - Elsevier
Rapid identification of viruses has important implications for medical healthcare. Current
methods for identification and quantification of particular virus are time consuming and often …
methods for identification and quantification of particular virus are time consuming and often …
Discovery of S-217622, a noncovalent oral SARS-CoV-2 3CL protease inhibitor clinical candidate for treating COVID-19
Y Unoh, S Uehara, K Nakahara, H Nobori… - Journal of medicinal …, 2022 - ACS Publications
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths and threatens …
syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths and threatens …
Anticancer, antioxidant, antiviral and antimicrobial activities of Kei Apple (Dovyalis caffra) fruit
Secondary plant metabolites remain one of the key sources of therapeutic agents despite
the development of new approaches for the discovery of medicinal drugs. In the current …
the development of new approaches for the discovery of medicinal drugs. In the current …
AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19
SS Good, J Westover, KH Jung, XJ Zhou… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
The impact of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the
causative agent of COVID-19, is global and unprecedented. Although remdesivir has …
causative agent of COVID-19, is global and unprecedented. Although remdesivir has …
SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells
M Sasaki, K Uemura, A Sato, S Toba, T Sanaki… - PLoS …, 2021 - journals.plos.org
The spike (S) protein of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)
binds to a host cell receptor which facilitates viral entry. A polybasic motif detected at the …
binds to a host cell receptor which facilitates viral entry. A polybasic motif detected at the …
In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine
We report on chloroquine, a 4-amino-quinoline, as an effective inhibitor of the replication of
the severe acute respiratory syndrome coronavirus (SARS-CoV) in vitro. Chloroquine is a …
the severe acute respiratory syndrome coronavirus (SARS-CoV) in vitro. Chloroquine is a …
Synthesis and antiviral activity of new pyrazole and thiazole derivatives
OI El-Sabbagh, MM Baraka, SM Ibrahim… - European journal of …, 2009 - Elsevier
New N-acetyl (5–8) and N-thiocarbamoyl (9–12) derivatives of 4, 5-dihydropyrazole were
synthesized starting from α, β-unsaturated ketones under the effect of hydrazine hydrate and …
synthesized starting from α, β-unsaturated ketones under the effect of hydrazine hydrate and …
Sulfated polysaccharides are potent and selective inhibitors of various enveloped viruses, including herpes simplex virus, cytomegalovirus, vesicular stomatitis virus …
M Baba, R Snoeck, R Pauwels… - Antimicrobial agents and …, 1988 - Am Soc Microbiol
Several sulfated polysaccharides (dextran sulfate, pentosan polysulfate, fucoidan, and
carrageenans) proved to be potent inhibitors for herpes simplex virus, human …
carrageenans) proved to be potent inhibitors for herpes simplex virus, human …
Design and synthesis of diselenobisbenzamides (DISeBAs) as nucleocapsid protein 7 (NCp7) inhibitors with anti-HIV activity
The interest in the synthesis of Se-containing compounds is growing with the discovery of
derivatives exhibiting various biological activities. In this manuscript, we have identified a …
derivatives exhibiting various biological activities. In this manuscript, we have identified a …