Long-acting injectable drugs for HIV-1 pre-exposure prophylaxis: considerations for Africa

E Moyo, G Murewanhema, G Musuka… - Tropical Medicine and …, 2022 - mdpi.com
Sub-Saharan Africa carries the highest burden of HIV-1 and AIDS. About 39% of all new
infections in the world in 2020 were in this region. Oral PrEP was found to be very effective …

Broadly neutralizing antibodies for HIV prevention: a comprehensive review and future perspectives

S Mahomed - Clinical Microbiology Reviews, 2024 - Am Soc Microbiol
The human immunodeficiency virus (HIV) epidemic remains a formidable global health
concern, with 39 million people living with the virus and 1.3 million new infections reported …

Continued attendance in a PrEP program despite low adherence and non-protective drug levels among adolescent girls and young women in Kenya: results from a …

JD Tapsoba, J Cover, C Obong'o, M Brady… - Plos …, 2022 - journals.plos.org
Background In sub-Saharan Africa (SSA), adolescent girls and young women (AGYW) ages
15 to 24 years represent< 10% of the population yet account for 1 in 5 new HIV infections …

Preferences and acceptability for long‐acting PrEP agents among pregnant and postpartum women with experience using daily oral PrEP in South Africa and Kenya

NJ Wara, R Mvududu, MM Marwa… - Journal of the …, 2023 - Wiley Online Library
Introduction Long‐acting pre‐exposure prophylaxis (PrEP) options could overcome barriers
to oral PrEP persistence during pregnancy and postpartum. We evaluated long‐acting PrEP …

Uptake of a patient‐centred dynamic choice model for HIV prevention in rural Kenya and Uganda: SEARCH SAPPHIRE study

J Kabami, E Kakande, G Chamie… - Journal of the …, 2023 - Wiley Online Library
Introduction Person‐centred HIV prevention delivery models that offer structured choices in
product, testing and visit location may increase coverage. However, data are lacking on the …

[HTML][HTML] Stability and bifurcation analysis of an HIV model with pre-exposure prophylaxis and treatment interventions

Z Chazuka, E Mudimu, D Mathebula - Scientific African, 2024 - Elsevier
Oral pre-exposure prophylaxis (PrEP) is a highly effective method of HIV prevention.
However, despite its effectiveness, the use of PrEP is not without challenges. These …

Integration of HIV pre-exposure prophylaxis (PrEP) services for pregnant and breastfeeding women in eight primary care clinics: results of an implementation science …

A Nelson, K Bheemraj, SS Dean, A de Voux… - BMC Global and Public …, 2024 - Springer
Background Although HIV vertical transmission has declined significantly in sub-Saharan
Africa, incident HIV infection in pregnant and postpartum women is estimated to account for …

Centring the health of women across the HIV research continuum

E Barr, LJ Marshall, LF Collins, C Godfrey, N St Vil… - The Lancet …, 2024 - thelancet.com
Despite tremendous advances in HIV research, women and gender diverse people—
particularly women from racial and ethnic groups under-represented in research …

The importance of assessing and addressing mental health barriers to PrEP use during pregnancy and postpartum in sub‐Saharan Africa: state of the science and …

AM Stanton, C O'Cleirigh, L Knight… - African Journal of …, 2022 - journals.lww.com
Introduction: Pregnant and postpartum women (PPW) in sub-Saharan Africa are at
disproportionately high risk of HIV infection compared to non-pregnant women. When used …

Safety surveillance for PrEP in pregnant and breastfeeding women

L Fairlie, D Lavies, E Kalk, O Mhlongo… - … in Reproductive Health, 2023 - frontiersin.org
The risk of HIV acquisition is higher during pregnancy and postpartum than other times.
Newly acquired maternal HIV infection associated with high primary viraemia, substantially …