Leading-edge regenerative medicine can take advantage of improved knowledge of key
roles played, both in stem cell fate determination and in cell growth/differentiation, by …

Oligodendrocytes (OLs) are the myelinating cells of the central nervous system (CNS) during
development and throughout adulthood. They result from a complex and well controlled …

Neurons require mechanisms to maintain ATP homeostasis in axons, which are highly
vulnerable to bioenergetic failure. Here, we elucidate a transcellular signaling mechanism …

Microglia are highly plastic immune cells which exist in a continuum of activation states. By
shaping the function of oligodendrocyte precursor cells (OPCs), the brain cells which …

Endogenous metabolites play essential roles in the regulation of cellular identity and activity.
Here we have investigated the process of oligodendrocyte precursor cell (OPC) …

Multiple sclerosis (MS) is a complex neurological condition that involves both inflammatory
demyelinating and neurodegenerative components. MS research and treatments have …

Carbon fixation from industrial flue gas with high concentrations of carbon dioxide (CO 2)
requires a comprehensive and systematic understanding of the physiological influences of …

Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system
(CNS), characterized by demyelination and neurodegeneration. Oligodendrocytes play a …

Background Agents promoting oligodendrocyte precursor cell differentiation have the
potential to restore halted and/or delayed remyelination in patients with multiple sclerosis …

Current efforts to find novel treatments that counteract multiple sclerosis (MS) have pointed
toward immunomodulation and remyelination. Currently, cell therapy has shown promising …