Synthetic photoswitches have been known for many years, but their usefulness in biology,
pharmacology, and medicine has only recently been systematically explored. Over the past …

The widespread use of molecular machines in biology has long suggested that great
rewards could come from bridging the gap between synthetic molecular systems and the …

Photopharmacology is an attractive approach for achieving targeted drug action with the use
of light. In photopharmacology, molecular photoswitches are introduced into the structure of …

Conspectus Light is a fascinating phenomenon that ties together physics, chemistry, and
biology. It is unmatched in its ability to confer information with temporal and spatial precision …

Light-controllable tools provide powerful means to manipulate and interrogate brain function
with relatively low invasiveness and high spatiotemporal precision. Although optogenetic …

Molecular photoswitches have attracted much attention in biological and materials contexts.
Despite the fact that existing classes of these highly interesting functional molecules have …

The last few years have witnessed significant advances in the use of light as a stimulus to
control biomolecular interactions. Great efforts have been devoted to the development of …

Cell-permeable photoswitchable small molecules, termed optojasps, are introduced to
optically control the dynamics of the actin cytoskeleton and cellular functions that depend on …

The covalent attachment of synthetic photoswitches is a general approach to impart light
sensitivity onto native receptors. It mimics the logic of natural photoreceptors and …

Photopharmacology aims to locally treat diseases and study biological processes with
photoresponsive drugs. Herein, easy access to photoswitchable drugs is crucial, which is …