Background Common Variable Immunodeficiency Disorders (CVID) encompass a spectrum
of immunodeficiency characterised by recurrent infections and diverse non-infectious …

Purpose Hypogammaglobulinemia in a context of lymphoma is usually considered as
secondary and prior lymphoma remains an exclusion criterion for a common variable …

Abstract Consanguineous marriages in Middle Eastern and North African (MENA) countries
are deeply-rooted tradition and highly prevalent resulting into increased prevalence of …

In recent years, gene-editing technologies have revolutionised precision medicine, and
human trials of this technology have been reported in cell-based cancer therapies and other …

Pulmonary involvement is the most common complication in patients with predominantly
antibody deficiencies (PADs). Therefore, patients require repeated imaging tests. Unlike …

More than 450 genetic defects result in inborn errors of immunity (IEI). Their individual
prevalence in specific cohorts is influenced by national characteristics and other factors. We …

Ιnborn errors of immunity (IEI) represents a heterogenous collection of> 480 immune system
anomalies, leading to severe infections, autoimmune disorders and malignancies. While …

Objective: This minireview gathers the scientific foundations of the literature on genetic
errors in the development of the humoral immune system to help pediatricians suspect these …

Primary immunodeficiencies or inborn errors of immunity (IEIs), are a group of more than
400 monogenic diseases that present with recurrent infections, immune dysregulation …

Measurement of anti-pneumococcal capsular polysaccharides (anti-PnPs) IgG titers is an
important tool in the immunologic assessment of patients with suspected immunodeficiency …